Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Samantha Pace"'
Autor:
Zheng Yang, James Loy, Brian Poirson, Yanshan Dai, Surendran Rajendran, Shihua Xu, Vanessa Spires, Murali Gururajan, Zheng Lin, Jaren Arbanas, Stephen Carl, Samantha Pace, Yun Wang, John Mehl, Krishna Vasudevan, Thomas Spires, Ruslan Novosiadly, Shodeinde Coker, Raymond Perez, Kelly Covello, Paul Morin, Robert Graziano, Miranda Broz, Lois Lehman-McKeeman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pharmacokinetic/pharmacodynamic (PK/PD) modeling was performed to quantitatively integrate preclinical pharmacology and toxicology data for determining the therapeutic index (TI) of an interleukin-10 (IL-10) fragment crystallizable (Fc) fusion protei
Externí odkaz:
https://doaj.org/article/ea7bedd2c46442b79708657bc96f6c3d
Autor:
Zheng, Yang, Surendran, Rajendran, Vanessa, Spires, Brian, Poirson, Murali, Gururajan, Zheng, Lin, Jaren, Arbanas, Stanley, Krystek, James, Loy, Yuan, Cheng, Stephen, Carl, Samantha, Pace, Yun, Wang, John, Mehl, Shihua, Xu, Krishna, Vasudevan, Miranda, Broz, Lois, Lehman-McKeeman, Paul, Morin, Robert F, Graziano
Publikováno v:
Drug Metabolism and Disposition. 50:898-908
Fragment crystallizable (Fc) fusion is commonly used for extending the half-life of biotherapeutics such as cytokines. In this work, we studied the pharmacokinetics of Fc-fused interleukin-10 (IL-10) proteins that exhibited potent antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10fbd6114f5d015011335019ef6b474
https://doi.org/10.1124/dmd.121.000799
https://doi.org/10.1124/dmd.121.000799
Publikováno v:
International Journal of Social Science Research and Review, Vol 4, Iss 2 (2021)
On March 11, 2020, the World Health Organisation (WHO) declared a global health pandemic, due to the spread of a novel coronavirus, later named “Covid-19”. The spread of Covid-19 led to social isolation, distancing and a number of restrictive mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41575fc6c40bc1d0f15cc2beb872de3
https://doi.org/10.47814/ijssrr.v4i2.88
https://doi.org/10.47814/ijssrr.v4i2.88
Autor:
Maria O. Ogunyankin, Samantha Pace, Prajnaparamita Dhar, David B. Volkin, Valerie Pringle, Neal Whitaker, Kimberly Merritt, Coleman Vaclaw
Publikováno v:
Journal of pharmaceutical sciences. 111(3)
Formation of submicron and subvisible protein particles (0.1-100 μm) present a major obstacle during processing and storage of therapeutic proteins. While protein aggregation resulting in particle formation is well-understood in bulk solution, the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6293b7bca978ad266c1183ba16b53be
https://pubmed.ncbi.nlm.nih.gov/34742729
https://pubmed.ncbi.nlm.nih.gov/34742729
Autor:
Samantha Pace
'Mon ado-rexie'témoigne du parcours de Samantha contre l'anorexie et le harcèlement scolaire. Des premières tentatives de suicide au chemin vers la guérison, le lecteur plonge dans sa vie et son combat. Elle vous laisse le soin de découvrir le s
Autor:
Phillip N. Rauk, Virginia R. Lupo, Ananta S Bangdiwala, Tana Kim, Samantha Pace, Sabrina C. Burn
Publikováno v:
American Journal of Obstetrics and Gynecology. 216:S253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25bc85863d0fc3b51967a7ec0a651873
https://doi.org/10.1016/j.ajog.2016.11.684
https://doi.org/10.1016/j.ajog.2016.11.684