Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Samantha O. Hasenleithner"'
Autor:
Isaac Lazzeri, Benjamin Gernot Spiegl, Samantha O. Hasenleithner, Michael R. Speicher, Martin Kircher
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3163-3174 (2024)
Motivation: The analysis of circulating cell-free DNA (cfDNA) holds immense promise as a non-invasive diagnostic tool across various human conditions. However, extracting biological insights from cfDNA fragments entails navigating complex and diverse
Externí odkaz:
https://doaj.org/article/27b524cbd63e445aa72d146cd881ec61
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-29 (2022)
Abstract Background The promise of precision cancer medicine presently centers around the genomic sequence of a patient’s tumor being translated into timely, actionable information to inform clinical care. The analysis of cell-free DNA from liquid
Externí odkaz:
https://doaj.org/article/1ddd844d862346628e1ca30081c7866a
Autor:
Jakob M. Riedl, Samantha O. Hasenleithner, Gudrun Pregartner, Lukas Scheipner, Florian Posch, Karin Groller, Karl Kashofer, Stephan W. Jahn, Thomas Bauernhofer, Martin Pichler, Herbert Stöger, Andrea Berghold, Gerald Hoefler, Michael R. Speicher, Ellen Heitzer, Armin Gerger
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for this purpose.
Externí odkaz:
https://doaj.org/article/6908822717ae4acb80b68f6cfaa4b07b
Publikováno v:
Cancer Cell. 40:1464-1466
Cell-free circulating DNA (cfDNA) analyses may enable multi-cancer early detection (MCED), but the most suitable method is unknown. In this issue of Cancer Cell, Jamshidi et al. compare ten machine-learning classifiers using various cfDNA features an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe21b65d6b47c43a2a6e381a35074b12
https://doi.org/10.1016/j.ccell.2022.11.009
https://doi.org/10.1016/j.ccell.2022.11.009
Autor:
Gudrun Pregartner, Gerald Hoefler, Stephan W Jahn, Lukas Scheipner, Ellen Heitzer, Samantha O Hasenleithner, Herbert Stöger, Karin Groller, Florian Posch, Martin Pichler, Karl Kashofer, Thomas Bauernhofer, Andrea Berghold, Jakob M. Riedl, Armin Gerger, Michael R. Speicher
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for this purpose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6027a7848df2811d7284addc97fb666e
https://opus.bibliothek.uni-augsburg.de/opus4/files/101638/1758835920987658.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/101638/1758835920987658.pdf
Autor:
Sabrina Weber, Harry J.M. Groen, Hylke C. Donker, Paul van der Leest, T. Jeroen N. Hiltermann, Menno Tamminga, Ellen Heitzer, Thomas Schlange, Grigory Sidorenkov, Wim Timens, Leon W.M.M. Terstappen, Ed Schuuring, Michael R. Speicher, Samantha O Hasenleithner, Ricarda Graf, Tina Moser, Benjamin Spiegl, Marie-Laure Yaspo
Publikováno v:
JCO Precision Oncology, 5(5), 1540-1553. AMER SOC CLINICAL ONCOLOGY
JCO Precision Oncology, 5, 1540-1553. American Society of Clinical Oncology
JCO Precision Oncology, 5, 1540-1553. AMER SOC CLINICAL ONCOLOGY
JCO Precision Oncology, 5, 1540-1553. American Society of Clinical Oncology
JCO Precision Oncology, 5, 1540-1553. AMER SOC CLINICAL ONCOLOGY
PURPOSE Immune checkpoint inhibitors (ICIs) are increasingly being used in non–small-cell lung cancer (NSCLC), yet biomarkers predicting their benefit are lacking. We evaluated if on-treatment changes of circulating tumor DNA (ctDNA) from ICI start
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cde702c93ab154b75a7806adec551d0
https://hdl.handle.net/11370/e14d18e8-e351-4424-95f3-52396f148084
https://hdl.handle.net/11370/e14d18e8-e351-4424-95f3-52396f148084
Autor:
Michael R. Speicher, Qing Zhou, Ellen Heitzer, Florian Posch, Karl Kashofer, Sabrina Weber, Ricarda Graf, Jasmin Alia Terzic, Helmut Schoellnast, Sigurd Lax, Julie Waldispuehl-Geigl, Samantha O Hasenleithner, Gerald Hoefler, Jelena Belic, Heinz Sill, Tina Moser, Thomas Bauernhofer, Jochen B. Geigl
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-7 (2020)
NPJ Precision Oncology
NPJ Precision Oncology
We addressed a significant unknown feature of circulating tumor DNA (ctDNA), i.e., how ctDNA levels change during chemotherapy, by serially monitoring ctDNA in patients with colorectal cancer during the 48-h application of FOLFOX. Surprisingly, we di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e11a76d5916547d68566e9f6ed4c9