Výsledky vyhledávání - "Samantha Morón-Ros"

Akademický článek

Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 599-613 (2022)

Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering

Externí odkaz: https://doaj.org/article/2318b693c0cb490ab904a421bf554622

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Akademický článek

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression

Autor: Jessica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Ferran Comas, Aina Lluch, Aleix Gavaldà-Navarro, Samantha Morón-Ros, Wifredo Ricart, Francesc Villarroya, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 870-879 (2022)

Lipopolysaccharide binding protein (Lbp) has been recently identified as a relevant component of innate immunity response associated to adiposity. Here, we aimed to investigate the impact of adipose tissue Lbp on weight gain and white adipose tissue

Externí odkaz: https://doaj.org/article/f9dbfee1ff5c4a26b586d69304553e65

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Akademický článek

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism

Publikováno v: Cell Reports, Vol 18, Iss 5, Pp 1241-1255 (2017)

Macrophages exert potent effector functions against invading microorganisms but constitute, paradoxically, a preferential niche for many bacterial strains to replicate. Using a model of infection by Salmonella Typhimurium, we have identified a molecu

Externí odkaz: https://doaj.org/article/439542872a5e4778b31f8b15c628ff56

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Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21

Autor: Rubén Cereijo, Ricardo Moure, Álvaro Hernáez, Francesc Villarroya, Laura Campderrós, Tania Quesada-López, Montserrat Cairó, Samantha Morón-Ros, Marta Giralt

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 320:E822-E834

Fibroblast growth factor-21 (FGF21) is a hormonal regulator of metabolism; it promotes glucose oxidation and the thermogenic capacity of adipose tissues. The levels of β-klotho (KLB), the co-receptor required for FGF21 action, are decreased in brown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bc13c1c5ab50aba4f3b517194845c6
https://doi.org/10.1152/ajpendo.00270.2020

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Specific adipose tissue

Autor: Jessica, Latorre, Francisco, Ortega, Núria, Oliveras-Cañellas, Ferran, Comas, Aina, Lluch, Aleix, Gavaldà-Navarro, Samantha, Morón-Ros, Wifredo, Ricart, Francesc, Villarroya, Marta, Giralt, José Manuel, Fernández-Real, José María, Moreno-Navarrete

Publikováno v: Molecular therapy. Nucleic acids. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b08320450acfcfe4c3c31f865a8f85aa
https://pubmed.ncbi.nlm.nih.gov/35141047

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FGF15/19 is required for adipose tissue plasticity in response to thermogenic adaptations

Autor: Samantha Morón-Ros, Matías A. Avila, Aleix Gavaldà-Navarro, José María Moreno-Navarrete, José Manuel Fernández-Real, Iker Uriarte, Carmen Berasain, Mònica Sabater-Masdeu, Francesc Villarroya, Marta Giralt

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Molecular Metabolism, 2021, vol. 43, art.núm. 101113
Articles publicats (IdIBGi)
DUGiDocs – Universitat de Girona
Molecular Metabolism

Objective To determine the role of enterokine FGF15/19 in adipose tissue thermogenic adaptations. Methods Circulating FGF19 and gene expression (qRT-PCR) levels were assessed in subcutaneous adipose tissue from obese human patients. Effects of experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1d43eb9ced0293170ba3b92e33838c
https://hdl.handle.net/10171/62043

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GPR120 controls neonatal brown adipose tissue thermogenic induction

Autor: Francesc Villarroya, Laura Campderrós, Roser Iglesias, Tania Quesada-López, Marta Giralt, Aleix Gavaldà-Navarro, Samantha Morón-Ros

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Adaptive induction of thermogenesis in brown adipose tissue (BAT) is essential for the survival of mammals after birth. We show here that G protein-coupled receptor protein 120 (GPR120) expression is dramatically induced after birth in mouse BAT. GPR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf3486428f02d673595268568d937a3
https://pubmed.ncbi.nlm.nih.gov/31361546

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Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice

Autor: José María Moreno-Navarrete, Marta Giralt, Samantha Morón-Ros, José Manuel Fernández-Real, Wifredo Ricart, Francisco Ortega, Aleix Gavaldà-Navarro, Aina Lluch, Amaia Rodríguez, Sara Becerril, Francesc Villarroya, Gema Frühbeck, Ferran Comas, Jèssica Latorre

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Chronic systemic low-level inflammation in metabolic disease is known to affect adipose tissue biology. Lysozyme (LYZ) is a major innate immune protein but its role in adipose tissue has not been investigated. Here, we aimed to investigate LYZ in hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1cbdb2b40ec1463213223ca9db92da
https://doi.org/10.1016/j.phrs.2021.105486

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CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation

Autor: Roser Iglesias, Teresa Mampel, Rubén Cereijo, Decio L. Eizirik, Jean Valéry Turatsinze, Francesc Villarroya, Marion Peyrou, Aleix Gavaldà-Navarro, Montserrat Cairó, Tania Quesada-López, David Sánchez-Infantes, Samantha Morón-Ros, Joan Villarroya, Marta Giralt

Publikováno v: Cell Metabolism, 28 (5
Cell Metabolism
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
CELL METABOLISM
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

The beneficial effects of brown adipose tissue (BAT) are attributed to its capacity to oxidize metabolites and produce heat, but recent data suggest that secretory properties of BAT may also be involved. Here, we identify the chemokine CXCL14 (C-X-C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467670891bcb45a1b006b70b59635f7d
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/283840

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