Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samantha Marglous"'
Autor:
Yong Shen, Jeffrey M. Verboon, Yuannyu Zhang, Nan Liu, Yoon Jung Kim, Samantha Marglous, Satish K. Nandakumar, Richard A. Voit, Claudia Fiorini, Ayesha Ejaz, Anindita Basak, Stuart H. Orkin, Jian Xu, Vijay G. Sankaran
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Genetic mechanisms underlying fetal hemoglobin (HbF) regulation and switching are not fully understood. Here, the authors develop a single-cell genome editing functional assay to model how effects of mutation-harbouring functional elements contribute
Externí odkaz:
https://doaj.org/article/6510aaea4b7a4bf494e21f0d26b79c2e
Autor:
Kara M. Gillmann, J. Sebastian Temme, Samantha Marglous, Claire E. Brown, Jeffrey C. Gildersleeve
Publikováno v:
Current Opinion in Chemical Biology. 74:102281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c1163d93acd1636baa19b69900d0ff5
https://doi.org/10.1016/j.cbpa.2023.102281
https://doi.org/10.1016/j.cbpa.2023.102281
Autor:
Nan Liu, Jian Xu, Stuart H. Orkin, Anindita Basak, Claudia Fiorini, Samantha Marglous, Vijay G. Sankaran, Satish K. Nandakumar, Yoon Jung Kim, Yuannyu Zhang, Richard A. Voit, Ayesha Ejaz, Yong Shen, Jeffrey M. Verboon
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Key mechanisms of fetal hemoglobin (HbF) regulation and switching have been elucidated through studies of human genetic variation, including mutations in the HBG1/2 promoters, deletions in the β-globin locus, and variation impacting BCL11A. While th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978c47c01868a32ffcc40bae3b340f70
https://pubmed.ncbi.nlm.nih.gov/34404810
https://pubmed.ncbi.nlm.nih.gov/34404810