Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Samantha Maragh"'
Autor:
Lili Wang, Samantha Maragh, Edward Kwee, Jamie L. Almeida, Sierra D. Miller, Tara Eskandari, Sheng Lin-Gibson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101219- (2024)
Externí odkaz:
https://doaj.org/article/30a56fe3a0d64e83a434cfff878d3ede
Publikováno v:
BioTechniques, Vol 72, Iss 6, Pp 279-286 (2022)
Although several genome editing options are available, CRISPR/Cas9 is one of the most commonly used systems for protein and advanced therapies. There are some long-term data regarding genomic and phenotypic stability, however, information is sparse.
Externí odkaz:
https://doaj.org/article/b81dd08a12bf454b99352c69fd259333
Autor:
Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Cell-based immunotherapies have had remarkable success in the clinic, specifically in the treatment of hematologic malignancies. However, these strategies have had limited efficacy in patients with solid tumors. To better understand the challenges in
Externí odkaz:
https://doaj.org/article/f4500c9773db47d7abfb74eccac2d857
Autor:
Samantha Maragh, Ronald A Miller, Seneca L Bessling, Guangliang Wang, Paul W Hook, Andrew S McCallion
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105460 (2014)
We recently demonstrated that the gene encoding the RNA binding motif protein 24 (RBM24) is expressed during mouse cardiogenesis, and determined the developmental requirement for its zebrafish homologs Rbm24a and Rbm24b during cardiac development. We
Externí odkaz:
https://doaj.org/article/19923f51d5944c0f8593affd21b16b06
Autor:
Maria Ximena Sosa, I K Ashok Sivakumar, Samantha Maragh, Vamsi Veeramachaneni, Ramesh Hariharan, Minothi Parulekar, Karin M Fredrikson, Timothy T Harkins, Jeffrey Lin, Andrew B Feldman, Pramila Tata, Georg B Ehret, Aravinda Chakravarti
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 10, p e1002737 (2012)
We describe methods for rapid sequencing of the entire human mitochondrial genome (mtgenome), which involve long-range PCR for specific amplification of the mtgenome, pyrosequencing, quantitative mapping of sequence reads to identify sequence variant
Externí odkaz:
https://doaj.org/article/1bf1abfb3b8d4eb796a4ed4b445b9237
Autor:
Simona Patange, Samantha Maragh
Publikováno v:
Biochemistry.
Genome editing is a rapidly evolving biotechnology with the potential to transform many sectors of industry such as agriculture, biomanufacturing, and medicine. This technology is enabled by an ever-growing portfolio of biomolecular reagents that spa
Autor:
Ross C. Wilson, Kevin D. Wells, W. Mark Saltzman, Philip J. Santangelo, Guohua Yi, Aravind Asokan, Shengdar Q. Tsai, Nenad Bursac, R. Holland Cheng, Shaoqin Gong, Gang Bao, Jennifer A. Doudna, Venkata S. Sabbisetti, Jarryd M. Campbell, Ryuji Morizane, Charles A. Gersbach, Mary E. Dickinson, Jon D. Hennebold, Kit S. Lam, Zheng-Yi Chen, John T. Hinson, Melinda R. Dwinell, Daniel G. Anderson, William R. Lagor, Qiaobing Xu, Melissa C. Skala, Jennifer A. Lewis, David J. Segal, Samantha Maragh, Guoping Feng, Stephen C. Ekker, Benjamin E. Deverman, Jonathan K. Watts, Alice F. Tarantal, Moriel H. Vandsburger, George A. Truskey, Ionita Ghiran, Marina E. Emborg, Jeff W.M. Bulte, Scot A. Wolfe, James E. Dahlman, Niren Murthy, Paul B. McCray, Erik J. Sontheimer, John C. Tilton, David T. Curiel, Benjamin S. Freedman, Guangping Gao, Mary Shimoyama, Kam W. Leong, Jiangbing Zhou, P. J. Brooks, Samira Kiani, Krystof S. Bankiewicz, Karl J. Clark, Jillian F. Banfield, Jon E. Levine, Krishanu Saha, Todd C. McDevitt, David R. Liu, Randall S. Prather, Daniel F. Carlson, Peter M. Glazer, Elliot L. Chaikof, Jason D. Heaney, Subhojit Roy, John A. Ronald, Stephen A. Murray, Cathleen M. Lutz, Anastasia Khvorova, Wen Xue, Sushmita Roy, Oleg Mirochnitchenko, Danith H. Ly, David M. Gamm
Publikováno v:
Nature
The move from reading to writing the human genome offers new opportunities to improve human health. The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer and mo
Autor:
Ionita Ghiran, Elzafir Elsheikh, Samantha Maragh, Bryant C. Nelson, Jennifer Jones, Paul C. DeRose, Lili Wang, Wyatt N. Vreeland
Publikováno v:
Nanomedicine (Lond)
Extracellular vesicles (EVs), such as exosomes and microvesicles, are nonreplicating lipid bilayer particles shed by most cell types which have the potential to revolutionize the development and efficient delivery of clinical therapeutics. This artic
Autor:
Eleanor Cowley, Shengdar Q. Tsai, Jian Ma, Yang Yang, Natalia G. Kolmakova, Ruochi Zhang, Samantha Maragh, Evgheni Strelcov, Giedre Krenciute, Christopher T. Petersen, GaHyun Lee, Yong Cheng, Cicera R. Lazzarotto, Xin Lan, Kasey Jividen, Varun Katta, Nikolay L. Malinin, Qian Qi, Yichao Li, Yanghua He
Publikováno v:
Nature biotechnology
Current methods can illuminate the genome-wide activity of CRISPR–Cas9 nucleases, but are not easily scalable to the throughput needed to fully understand the principles that govern Cas9 specificity. Here we describe ‘circularization for high-thr
Autor:
Gretchen Greene, Jared Ragland, Zachary Trautt, June W. Lau, Raymond Plante, Joshua Taillon, Adam Abel Creuziger, Chandler A. Becker, Joe Bennett, Niksa Blonder, Lisa Borsuk, Carelyn E. Campbell, Adam Friss, Lucas Hale, Michael Halter, Robert Hanisch, Gary R. Hardin, Lyle E. Levine, Samantha Maragh, Sierra Miller, Chris Muzny, Marcus William Newrock, John Perkins, Anne L. Plant, Bruce D. Ravel, David J. Ross, John Henry J. Scott, Christopher Szakal, Alessandro Tona, Peter Vallone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c47a82e2fe3ea032ff833938837b714
https://doi.org/10.6028/nist.tn.2216
https://doi.org/10.6028/nist.tn.2216