Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha M. South"'
Autor:
Vince W. Clark, Bruno P. Meloni, Neville W Knuckey, Rajiv Bhalla, Ryan S. Anderton, Karine Mardon, Li Shan Chiu, Samantha M South
Publikováno v:
Future Drug Discovery. 2
Aim: R18D is a poly-arginine peptide that has demonstrated neuroprotection in preclinical models of excitotoxicity, stroke, hypoxic-ischemic encephalopathy and traumatic brain injury. Here, we examined the peptide’s uptake in serum. Materials & met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10561da408ef6b6eb9d20a31e1bba717
https://doi.org/10.4155/fdd-2019-0039
https://doi.org/10.4155/fdd-2019-0039
Autor:
Ryan S. Anderton, Samantha M South, Joseph Y. Nashed, Frank L. Mastaglia, Bruno P. Meloni, David Blacker, Andrew Winterborn, Neville W. Knuckey, Yining Chen, Douglas J. Cook, Kathleen A. Harrison
Publikováno v:
Neurotherapeutics
Poly-arginine peptide-18 (R18) is neuroprotective in different rodent middle cerebral artery occlusion (MCAO) stroke models. In this study, we examined whether R18 treatment could reduce ischemic brain injury and improve functional outcome in a nonhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f205ec8d40d6f29725c802531a8d8c8d
https://europepmc.org/articles/PMC7283416/
https://europepmc.org/articles/PMC7283416/
Autor:
Amber L. Marriott, Neville W. Knuckey, David Blacker, Angela Jacques, Robert A. Déziel, Samantha M South, Daphne A. Gill, Bruno P. Meloni
Publikováno v:
Stroke. 50
Aims: We have previously demonstrated that the poly-arginine peptides R18 and R18D are neuroprotective at 24 hours following intraluminal middle cerebral artery occlusion (MCAO) in the rat. Therefore, using an independent laboratory we examined the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6e5a18eac7bbc49f07d32d30af8421
https://doi.org/10.1161/str.50.suppl_1.wp156
https://doi.org/10.1161/str.50.suppl_1.wp156
Autor:
Ryan Reinders, Samantha M South, Bruno P. Meloni, Neville W. Knuckey, Lane J Liddle, David Blacker, Frederick Colbourne
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0224870 (2019)
PLoS ONE, Vol 14, Iss 11, p e0224870 (2019)
Background Cationic arginine-rich peptides (CARPs) have demonstrated neuroprotective and/or behavioural efficacy in ischemic and hemorrhagic stroke and traumatic brain injury models. Therefore, in this study we investigated the safety and neuroprotec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9a2ce022b6fff36f92100c59d00a41
https://doi.org/10.1371/journal.pone.0224870
https://doi.org/10.1371/journal.pone.0224870
Autor:
Qinghao Xu, Michael J. Glass, Laarni Quimson, Samantha M. South, Deborah M. Hegarty, Martin Oselkin, Virginia M. Pickel, Charles E. Inturrisi
Publikováno v:
Experimental Neurology. 213:57-70
Preclinical behavioral pharmacological and neuropharmacological evidence indicates that the NMDA receptor plays an important role in opioid dependence, however, the neural substrates subserving these actions are poorly understood. The central nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0664e4e32f57a32c417928258b536638
https://doi.org/10.1016/j.expneurol.2008.04.045
https://doi.org/10.1016/j.expneurol.2008.04.045
Autor:
Hsinlin T Cheng, Qinghao Xu, Megumi Ohata, Samantha M. South, Masahiro Suzuki, Deborah M. Hegarty, Amanda R. Weyerbacher, Charles E. Inturrisi
Publikováno v:
Neuroscience. 155:948-958
The N-methyl-d-aspartate (NMDA) receptor in the spinal cord dorsal horn (SCDH) is one of the mechanisms involved in central sensitization during chronic pain. Previously, this laboratory created a spatio-temporal knockout (KO) of the N-methyl-d-aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd13631be14a392398d6af7b39932b
https://doi.org/10.1016/j.neuroscience.2008.06.024
https://doi.org/10.1016/j.neuroscience.2008.06.024
Publikováno v:
The Journal of Pain. 6:809-816
For the pharmacokinetic evaluation of Silastic capsules, ovariectomized (OVX) rats were implanted subcutaneously with this dosage form containing 17beta-estradiol (5, 10, 15, or 20% in cholesterol, where 5% 17beta-estradiol equals 0.4 mg) or progeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fcd6d3d3198dfd4bb382fcc026ac29
https://doi.org/10.1016/j.jpain.2005.07.007
https://doi.org/10.1016/j.jpain.2005.07.007
Autor:
Shirzad Jenab, Fred H. Gage, Johanna J. Bogulavsky, Andreas W. Sailer, Tony L. Yaksh, Megumi Ohata, Stephen F. Heinemann, Samantha M. South, Tatsuro Kohno, Shelle Malkmus, Charles E. Inturrisi, Carrie T. Drake, Bryce Vissel, Brian K. Kaspar, Deborah M. Hegarty, Philip J. Horner, Takashi Masuyama, Clifford J. Woolf
Publikováno v:
The Journal of Neuroscience. 23:5031-5040
To determine the importance of the NMDA receptor (NMDAR) in pain hypersensitivity after injury, the NMDAR1 (NR1) subunit was selectively deleted in the lumbar spinal cord of adult mice by the localized injection of an adenoassociated virus expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84c7aadfbfe01fb83f64a2f56d50be9
https://doi.org/10.1523/jneurosci.23-12-05031.2003
https://doi.org/10.1523/jneurosci.23-12-05031.2003
Publikováno v:
The journal of pain. 8(4)
A subcutaneous implant of 17β-estradiol or progesterone provides steady-state serum hormone levels from 7 to 24 days after implantation and allows the evaluation of the effects of the replacement with these hormones on phase 1 and phase 2 formalin-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6533be8313833f094399d6dd782a187
https://pubmed.ncbi.nlm.nih.gov/17140856
https://pubmed.ncbi.nlm.nih.gov/17140856