Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Samantha M. Reiss"'
Autor:
Rym Ben-Othman, Bing Cai, Aaron C. Liu, Natallia Varankovich, Daniel He, Travis M. Blimkie, Amy H. Lee, Erin E. Gill, Mark Novotny, Brian Aevermann, Sibyl Drissler, Casey P. Shannon, Sarah McCann, Kim Marty, Gordean Bjornson, Rachel D. Edgar, David Tse Shen Lin, Nicole Gladish, Julia Maclsaac, Nelly Amenyogbe, Queenie Chan, Alba Llibre, Joyce Collin, Elise Landais, Khoa Le, Samantha M. Reiss, Wayne C. Koff, Colin Havenar-Daughton, Manraj Heran, Bippan Sangha, David Walt, Mel Krajden, Shane Crotty, Devin Sok, Bryan Briney, Dennis R. Burton, Darragh Duffy, Leonard J. Foster, William W. Mohn, Michael S. Kobor, Scott J. Tebbutt, Ryan R. Brinkman, Richard H. Scheuermann, Robert E. W. Hancock, Tobias R. Kollmann, Manish Sadarangani
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major failures in vaccine development and we still do not have highly effective licensed vaccines for tuberc
Externí odkaz:
https://doaj.org/article/161a4130886644838de4892cc5710d1d
Autor:
Amit A. Upadhyay, Robert C. Kauffman, Amber N. Wolabaugh, Alice Cho, Nirav B. Patel, Samantha M. Reiss, Colin Havenar-Daughton, Reem A. Dawoud, Gregory K. Tharp, Iñaki Sanz, Bali Pulendran, Shane Crotty, F. Eun-Hyung Lee, Jens Wrammert, Steven E. Bosinger
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract B cells play a critical role in the immune response by producing antibodies, which display remarkable diversity. Here we describe a bioinformatic pipeline, BALDR (BCR Assignment of Lineage using D e novo Reconstruction) that accurately recon
Externí odkaz:
https://doaj.org/article/35259f58e6db4d65a3996e49c0968a7d
Autor:
Daniel W. Kulp, Jon M. Steichen, Matthias Pauthner, Xiaozhen Hu, Torben Schiffner, Alessia Liguori, Christopher A. Cottrell, Colin Havenar-Daughton, Gabriel Ozorowski, Erik Georgeson, Oleksandr Kalyuzhniy, Jordan R. Willis, Michael Kubitz, Yumiko Adachi, Samantha M. Reiss, Mia Shin, Natalia de Val, Andrew B. Ward, Shane Crotty, Dennis R. Burton, William R. Schief
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Eliciting broadly neutralizing antibodies (bnAbs) is a primary HIV vaccine goal, but available immunogens expose epitopes for development of non-nAbs. Here, the authors use computational and structure-guided design to develop improved native-like env
Externí odkaz:
https://doaj.org/article/e45b30de0325403bb21de6e2ce224daa
Autor:
Colin Havenar-Daughton, Diane G. Carnathan, Archana V. Boopathy, Amit A. Upadhyay, Ben Murrell, Samantha M. Reiss, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Pallavi Dhadvai, Federico Viviano, Kirti Kaushik, Jinal N. Bhiman, Bryan Briney, Dennis R. Burton, Steven E. Bosinger, William R. Schief, Darrell J. Irvine, Guido Silvestri, Shane Crotty
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1756-1766.e8 (2019)
Summary: The first immunization in a protein prime-boost vaccination is likely to be critical for how the immune response unfolds. Using fine needle aspirates (FNAs) of draining lymph nodes (LNs), we tracked the kinetics of the primary immune respons
Externí odkaz:
https://doaj.org/article/4bfc82547cda434c9a02cab1bdb35528
Autor:
Matthias G, Pauthner, Joseph P, Nkolola, Colin, Havenar-Daughton, Ben, Murrell, Samantha M, Reiss, Raiza, Bastidas, Jérémie, Prévost, Rebecca, Nedellec, Benjamin, von Bredow, Peter, Abbink, Christopher A, Cottrell, Daniel W, Kulp, Talar, Tokatlian, Bartek, Nogal, Matteo, Bianchi, Hui, Li, Jeong Hyun, Lee, Salvatore T, Butera, David T, Evans, Lars, Hangartner, Andrés, Finzi, Ian A, Wilson, Richard T, Wyatt, Darrell J, Irvine, William R, Schief, Andrew B, Ward, Rogier W, Sanders, Shane, Crotty, George M, Shaw, Dan H, Barouch, Dennis R, Burton
Publikováno v:
Immunity, 50(1), 241-252.e6. Cell Press
Immunity
Immunity
Summary Passive administration of HIV neutralizing antibodies (nAbs) can protect macaques from hard-to-neutralize (tier 2) chimeric simian-human immunodeficiency virus (SHIV) challenge. However, conditions for nAb-mediated protection after vaccinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1e905e0b0b45fe979f6c4170b3072205
https://pure.amc.nl/en/publications/vaccineinduced-protection-from-homologous-tier-2-shiv-challenge-in-nonhuman-primates-depends-on-serumneutralizing-antibody-titers(14094cdb-6095-47d4-9e26-ac8d7196b3e7).html
https://pure.amc.nl/en/publications/vaccineinduced-protection-from-homologous-tier-2-shiv-challenge-in-nonhuman-primates-depends-on-serumneutralizing-antibody-titers(14094cdb-6095-47d4-9e26-ac8d7196b3e7).html
Autor:
Kirti Kaushik, Amit A. Upadhyay, Ben Murrell, Etse H. Gebru, Pallavi Dhadvai, William R. Schief, Bryan Briney, Darrell J. Irvine, Colin Havenar-Daughton, Federico Viviano, Guido Silvestri, Yury Chloe, Steven E. Bosinger, Samantha M. Reiss, Dennis R. Burton, Archana V. Boopathy, Diane G. Carnathan, Chiamaka A. Enemuo, Shane Crotty
Publikováno v:
SSRN Electronic Journal.
The first immunization in a protein prime-boost vaccination is likely to be a critical event for how the immune response unfolds. However, priming immunizations generally produce little circulating antibody (Ab) or T cell responses in blood and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339f0e6b0cfdf1c4c471788c1b752a59
https://doi.org/10.2139/ssrn.3387660
https://doi.org/10.2139/ssrn.3387660
Autor:
Guido Silvestri, Patricia van der Woude, Ata Ur Rasheed Mohammed, Dennis R. Burton, Anapatricia Garcia, Colin Havenar-Daughton, Michela Locci, Diane G. Carnathan, Samantha M. Reiss, Steven W. de Taeye, Bali Pulendran, Alba Torrents de la Peña, Marit J. van Gils, Jessica Huang, Devin Sok, Khoa M. Le, Jennifer S. Wood, Sudhir Pai Kasturi, Sanjeev Gumber, Rafi Ahmed, Sandy L. Rosales, Shane Crotty, Bryan Briney, Grégory Seumois, Matthias Pauthner, Rogier W. Sanders, Kirti Kaushik, John P. Moore
Publikováno v:
Cell reports, 17(9), 2195-2209. Cell Press
SummaryGenerating tier 2 HIV-neutralizing antibody (nAb) responses by immunization remains a challenging problem, and the immunological barriers to induction of such responses with Env immunogens remain unclear. Here, some rhesus monkeys developed au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb937435369a7312e9cb5f1a9e93b11
https://doi.org/10.1016/j.celrep.2016.10.085
https://doi.org/10.1016/j.celrep.2016.10.085
Autor:
Bali Pulendran, Samantha M. Reiss, Guido Silvestri, Kayla Kendric, Alba Torrents de la Peña, Jennifer M. Dan, Shane Crotty, Sudhir Pai Kasturi, Jennifer E. Wu, Marcella Bothwell, Colin Havenar-Daughton, Diane G. Carnathan, Rogier W. Sanders
Publikováno v:
Journal of immunology (Baltimore, Md., 197(3), 994-1002. American Association of Immunologists
A range of current candidate AIDS vaccine regimens are focused on generating protective HIV-neutralizing Ab responses. Many of these efforts rely on the rhesus macaque animal model. Understanding how protective Ab responses develop and how to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d4b9fe318a62c888f709765aac4b24
https://doi.org/10.4049/jimmunol.1600320
https://doi.org/10.4049/jimmunol.1600320
Autor:
Farnaz Hasteh, Shane Crotty, Somaye Y. Zare, Gina Levi, Min Ji Suh, Colin Havenar-Daughton, Isabel G. Newton, Brittany Schwan, Samantha M. Reiss
Publikováno v:
J Immunol Methods
Germinal centers (GC) are critically important for maturation of the antibody response and generation of memory B cells, processes that form the basis for long-term protection from pathogens. GCs only occur in lymphoid tissue, such as lymph nodes, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e054576070ef504dfbbb01f1f5c75a3
https://doi.org/10.1016/j.jim.2020.112746
https://doi.org/10.1016/j.jim.2020.112746
Autor:
Chiamaka A. Enemuo, Mariane B. Melo, Nirav B. Patel, Matthias Pauthner, Kimberly M. Cirelli, Etse H. Gebru, Andrew B. Ward, Amit A. Upadhyay, Dennis R. Burton, Daniel W. Kulp, William R. Schief, Benjamin Cossette, Federico Viviano, Venkatesh Kumar, Guido Silvestri, Jacob T. Martin, Steven E. Bosinger, Catherine Nakao, Diane G. Carnathan, William S. Gibson, Christopher A. Cottrell, Melissa Smith, Corey T. Watson, Bartek Nogal, Ben Murrell, Amber N. Wolabaugh, Darrell J. Irvine, Oscar L. Rodriguez, Yury Choe, Raiza Bastidas, Talar Tokatlian, Sergey Menis, Shane Crotty, Samantha M. Reiss
Publikováno v:
Cell
PMC
PMC
Conventional immunization strategies will likely be insufficient for the development of a broadly neutralizing antibody (bnAb) vaccine for HIV or other difficult pathogens because of the immunological hurdles posed, including B cell immunodominance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9809e096b1fdda1949d8da30d6e8a6eb
https://doi.org/10.1016/j.cell.2019.12.027
https://doi.org/10.1016/j.cell.2019.12.027