Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samantha M, Prezioso"'
Autor:
Jennifer M. Peña, Samantha M. Prezioso, Kirsty A. McFarland, Tracy K. Kambara, Kathryn M. Ramsey, Padraig Deighan, Simon L. Dove
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an anti
Externí odkaz:
https://doaj.org/article/b438ab3975a44616a29582404e1b10c2
Autor:
Joanna B. Goldberg, Debayan Dey, Samantha M. Prezioso, Emily G. Kuiper, Paige A. LaMore, Joshua P. Owings, Graeme L. Conn
Publikováno v:
Journal of Biological Chemistry. 294:20109-20121
The opportunistic bacterial pathogen Pseudomonas aeruginosa is a leading cause of serious infections in individuals with cystic fibrosis, compromised immune systems, or severe burns. P. aeruginosa adhesion to host epithelial cells is enhanced by surf
Autor:
Simon L. Dove, Kirsty A. McFarland, Kathryn M. Ramsey, Jennifer M. Peña, Tracy K. Kambara, Samantha M. Prezioso, Padraig Deighan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In Pseudomonas aeruginosa the alp system encodes a programmed cell death pathway that is switched on in a subset of cells in response to DNA damage and is linked to the virulence of the organism. Here we show that the central regulator of this pathwa
Publikováno v:
Molecular Microbiology. 106:22-34
Elfamycins are a relatively understudied group of antibiotics that target the essential process of translation through impairment of EF-Tu function. For the most part, the utility of these compounds has been as laboratory tools for the study of EF-Tu
Autor:
Emily G, Kuiper, Debayan, Dey, Paige A, LaMore, Joshua P, Owings, Samantha M, Prezioso, Joanna B, Goldberg, Graeme L, Conn
Publikováno v:
J Biol Chem
The opportunistic bacterial pathogen Pseudomonas aeruginosa is a leading cause of serious infections in individuals with cystic fibrosis, compromised immune systems, or severe burns. P. aeruginosa adhesion to host epithelial cells is enhanced by surf
Autor:
Debayan Dey, Paige A. LaMore, Samantha M. Prezioso, Joanna B. Goldberg, Emily G. Kuiper, Joshua P. Owings, Graeme L. Conn
Pseudomonas aeruginosa is an opportunistic pathogen and a leading cause of serious infections in individuals with cystic fibrosis, compromised immune systems, and severe burns. During infection, P. aeruginosa adhesion to host epithelial cells is enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a4934ad1d858d456e281b64c3c583e
https://doi.org/10.1101/773556
https://doi.org/10.1101/773556
Autor:
Allen L. Hsu, Brady A. Travis, Thomas Tallo, Simon L. Dove, Alberto Bartesaghi, Kathryn M. Ramsey, Mario J. Borgnia, Jamie M. Wandzilak, Richard G. Brennan, Maria A. Schumacher, Samantha M. Prezioso
Publikováno v:
Molecular Cell. 81:139-152.e10
Summary The bacterium Francisella tularensis (Ft) is one of the most infectious agents known. Ft virulence is controlled by a unique combination of transcription regulators: the MglA-SspA heterodimer, PigR, and the stress signal, ppGpp. MglA-SspA ass
Autor:
Sebastián Albertí, Joanna B. Goldberg, Emily G. Kuiper, Samantha M. Prezioso, Duc M. Duong, Graeme L. Conn, Qiudong Deng
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The Pseudomonas aeruginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-translational modification important for initial bacterial adherence to host epithelial cells. EftM methyltransferase activity is
Autor:
Lisa G. McWilliams, Andrew J. Carter, Samantha M. Prezioso, David M. Schieltz, Sara C. McGrath, Stephen A. Morse, John R. Barr, Yulanda M. Williamson, Zsuzsanna Kuklenyik
Publikováno v:
Toxicon : official journal of the International Society on Toxinology
The seeds of the Ricinus communis (Castor bean) plant are the source of the economically important commodity castor oil. Castor seeds also contain the proteins ricin and R. communis agglutinin (RCA), two toxic lectins that are hazardous to human heal
Autor:
Segaran P. Pillai, Erin Swaney, Kristin W. Prentice, Andrea Staab, Cheryl Gauthier, Ian A Elder, Richard B Kellogg, David R. Hodge, Stephen A. Morse, Peter L. Estacio, Gerald Kovacs, Uma Basavanna, Samantha M. Prezioso, Denise Pettit, Rebecca Hastings, Eric A. E. Garber, Brenda S Morse, Shashi Sharma, Tanya Swanson, Jason G Ramage, Rahsaan Drumgoole, Larry H. Stanker, Shomik Datta
Publikováno v:
Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science. 11:237-250
Ricin, a heterodimeric toxin that is present in the seeds of the Ricinus communis plant, is the biothreat agent most frequently encountered by law enforcement agencies in the United States. Even in untrained hands, the easily obtainable seeds can yie