Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Samantha Leier"'
Autor:
Nasim Sarrami, Bryce Nelson, Samantha Leier, John Wilson, Conrad Chan, Jalna Meens, Teesha Komal, Laurie Ailles, Melinda Wuest, Michael Schultz, Afsaneh Lavasanifar, Raymond M. Reilly, Frank Wuest
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background The objective of this research was the development and evaluation of 203Pb-labelled panitumumab (203Pb-PSC-panitumumab) as an immuno-SPECT radioligand for the detection of EGFR + head and neck squamous cell carcinoma (HNSCC) in a
Externí odkaz:
https://doaj.org/article/dbec871ee73f42fbb3a3914c8584d87c
Autor:
Samantha Leier, Frank Wuest
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1270 (2024)
Background: The incorporation of radionuclides into peptides and larger biomolecules requires efficient and sometimes biorthogonal reaction conditions, to which click chemistry provides a convenient approach. Methods: Traditionally, click-based radio
Externí odkaz:
https://doaj.org/article/541ab2e439254ffcba35a49b6a5cb521
Publikováno v:
ACS Omega, Vol 4, Iss 26, Pp 22101-22107 (2019)
Externí odkaz:
https://doaj.org/article/02f6a00c91a34e0dba95b5648ebd79fe
Autor:
Mohammad Reza Vakili, Michael Weinfeld, Melinda Wuest, Igor M. Paiva, Frank Wuest, Samantha Leier, Stephanie Mattingly, Afsaneh Lavasanifar
Publikováno v:
Molecular Pharmaceutics. 17:1470-1481
Polymeric micellar nanoparticles represent versatile and biocompatible platforms for targeted drug delivery. However, tracking their biodistribution, stability, and clearance profile in vivo is challenging. The goal of this study was to prepare surfa
Publikováno v:
ACS Omega
ACS Omega, Vol 4, Iss 26, Pp 22101-22107 (2019)
ACS Omega, Vol 4, Iss 26, Pp 22101-22107 (2019)
Tyrosine is an attractive target for chemo- and site-selective protein modification. The particular chemical nature of tyrosine residues allows bioconjugation chemistry with reactive aryl diazonium salts via electrophilic aromatic substitution to pro
Publikováno v:
Nuclear Medicine and Biology. :S156
Autor:
Igor, Paiva, Stephanie, Mattingly, Melinda, Wuest, Samantha, Leier, Mohammad Reza, Vakili, Michael, Weinfeld, Afsaneh, Lavasanifar, Frank, Wuest
Publikováno v:
Molecular pharmaceutics. 17(5)
Polymeric micellar nanoparticles represent versatile and biocompatible platforms for targeted drug delivery. However, tracking their biodistribution, stability, and clearance profile in vivo is challenging. The goal of this study was to prepare surfa