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of 4
pro vyhledávání: '"Samantha L. Coss"'
Autor:
Johanna M. Seddon, Dikha De, William Casazza, Shun-Yun Cheng, Claudio Punzo, Mark Daly, Danlei Zhou, Samantha L. Coss, John P. Atkinson, Chack-Yung Yu
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Introduction: Age-related macular degeneration (AMD) is the leading cause of central vision loss in the elderly. One-third of the genetic contribution to this disease remains unexplained.Methods: We analyzed targeted sequencing data from two independ
Externí odkaz:
https://doaj.org/article/b3376f1811e74e0083f92b034e76bf47
Autor:
Samantha L. Coss, Danlei Zhou, Gilbert T. Chua, Rabheh Abdul Aziz, Robert P. Hoffman, Yee Ling Wu, Stacy P. Ardoin, John P. Atkinson, Chack-Yung Yu
Publikováno v:
Journal of autoimmunity.
Genetic deficiencies of early components of the classical complement activation pathway (especially C1q, r, s, and C4) are the strongest monogenic causal factors for the prototypic autoimmune disease systemic lupus erythematosus (SLE), but their prev
Autor:
Arash Grakoui, Samantha L. Coss, Christopher M. Walker, Jonathan R. Honegger, Almudena Torres-Cornejo, Georg M. Lauer, Mona Prasad, Melissa Moore-Clingenpeel
Publikováno v:
Journal of Clinical Investigation. 130:748-753
Chronic hepatitis C virus (HCV) infection is characterized by persistent high-level viremia and defective cellular immunity, including a lack of functional HCV-specific CD4+ T cells. We previously described an exceptional period of viral control that
Publikováno v:
Open Forum Infectious Diseases
Background Chronic hepatitis C virus (HCV) infection is marked by stable, high -level viremia and a failed T-cell response. HCV-specific CD4+ helper T cells are rare, and CD8+ cytotoxic T cells are functionally exhausted or ineffective due to viral e