Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha L. Bucktrout"'
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract For at least 300 years the immune system has been targeted to improve human health. Decades of work advancing immunotherapies against infection and autoimmunity paved the way for the current explosion in cancer immunotherapies. Pathways targ
Externí odkaz:
https://doaj.org/article/bbfea4ae2305489ca51d763f74dc7890
Autor:
Samantha L. Bucktrout, Nicholas E. Banovich, Lisa H. Butterfield, Cansu Cimen-Bozkus, Josephine R. Giles, Zinaida Good, Daniel Goodman, Vanessa D. Jonsson, Caleb Lareau, Alexander Marson, Denna M. Maurer, Paul V. Munson, Mike Stubbington, Sarah Taylor, Abbey Cutchin
Publikováno v:
Nature Medicine. 28:1761-1764
Autor:
Padmanee Sharma, James P. Allison, Ignacio I. Wistuba, Anirban Maitra, Shalini S. Yadav, Hao Zhao, Maria G. Higa, Jorge B. Scutti, Sumit K. Subudhi, Javier Chaparro-Riggers, Tao Sai, Edward Pascua, Terrence Park, John C. Lin, Ashley E. Mahne, Bevin M. Smith, Jorge Blando, Irina Fernandez Curbelo, Samantha L. Bucktrout, Luis Vence
Purpose:Determine the differential effect of a FcγR-binding, mIgG2a anti-GITR antibody in mouse tumor models, and characterize the tumor microenvironment for the frequency of GITR expression in T-cell subsets from seven different human solid tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160c22ead2ef40e11c9765bc9c16d2a9
https://doi.org/10.1158/1078-0432.c.6527769.v1
https://doi.org/10.1158/1078-0432.c.6527769.v1
Autor:
Padmanee Sharma, James P. Allison, Ignacio I. Wistuba, Anirban Maitra, Shalini S. Yadav, Hao Zhao, Maria G. Higa, Jorge B. Scutti, Sumit K. Subudhi, Javier Chaparro-Riggers, Tao Sai, Edward Pascua, Terrence Park, John C. Lin, Ashley E. Mahne, Bevin M. Smith, Jorge Blando, Irina Fernandez Curbelo, Samantha L. Bucktrout, Luis Vence
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5fd56d154ca75fb5b4911f57a73fb8
https://doi.org/10.1158/1078-0432.22471080.v1
https://doi.org/10.1158/1078-0432.22471080.v1
Autor:
Pamela D. Garzone, Gilbert Y. Wong, Chandrasekhar Udata, Samantha L. Bucktrout, Megan Shannon, Jason H. Williams, Bishu J Ganguly, Xu Meng, Matteo Levisetti, Tenshang Joh
Publikováno v:
The AAPS Journal
IL-7 receptor-α (IL-7Rα) blockade has been shown to reverse autoimmune diabetes in the non-obese diabetic mouse by promoting inhibition of effector T cells and consequently altering the balance of regulatory T (Treg) and effector memory (TEM) cells
Autor:
Kevan C. Herold, Gilbert Y. Wong, Tenshang Joh, Shobha Potluri, Peter A. Gottlieb, Bruce W. Bode, Matteo Levisetti, Janet B. McGill, Megan Shannon, Bishu J Ganguly, Jing W. Hughes, Samantha L. Bucktrout, Desmond A. Schatz, Stephen E. Gitelman, Jeremy Pettus, Xiao Wang, Pamela D. Garzone, Chandrasekhar Udata
Publikováno v:
JCI Insight. 4
BACKGROUND. The cytokine IL-7 is critical for T cell development and function. We performed a Phase Ib study in patients with type 1 diabetes (T1D) to evaluate how blockade of IL-7 would affect immune cells and relevant clinical responses. METHODS. T
Autor:
Jeffrey M. Granja, Kavita Y. Sarin, Daniel K. Wells, Kathryn E. Yost, Chunlin Wang, Howard Y. Chang, Mark M. Davis, Ryanne A. Brown, Anne Lynn S. Chang, Yanyan Qi, Katherine McNamara, Christina Curtis, Rohit Gupta, Ansuman T. Satpathy, Samantha L. Bucktrout, Robin Kageyama
Immunotherapies that block inhibitory checkpoint receptors on T cells have transformed the clinical care of cancer patients. However, which tumor-specific T cells are mobilized following checkpoint blockade remains unclear. Here, we performed paired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38d59db201d0c0f743eec7f7b62e91a
https://doi.org/10.1101/648899
https://doi.org/10.1101/648899
Autor:
Kathryn E, Yost, Ansuman T, Satpathy, Daniel K, Wells, Yanyan, Qi, Chunlin, Wang, Robin, Kageyama, Katherine L, McNamara, Jeffrey M, Granja, Kavita Y, Sarin, Ryanne A, Brown, Rohit K, Gupta, Christina, Curtis, Samantha L, Bucktrout, Mark M, Davis, Anne Lynn S, Chang, Howard Y, Chang
Publikováno v:
Nature medicine. 25(8)
Immunotherapies that block inhibitory checkpoint receptors on T cells have transformed the clinical care of patients with cancer
Autor:
Ashley Mahne, Javier Chaparro-Riggers, John C. Lin, Anirban Maitra, Irina Fernandez Curbelo, Maria Gisela Higa, Samantha L. Bucktrout, Jorge Augusto Borin Scutti, Shalini S. Yadav, Ignacio I. Wistuba, Jorge Blando, Tao Sai, Pascua Edward Derrick, Terrence Park, Padmanee Sharma, Smith Bevin Marie Brady, James P. Allison, Sumit K. Subudhi, Hao Zhao, Luis M Vence
Publikováno v:
Clin Cancer Res
Purpose: Determine the differential effect of a FcγR-binding, mIgG2a anti-GITR antibody in mouse tumor models, and characterize the tumor microenvironment for the frequency of GITR expression in T-cell subsets from seven different human solid tumors