Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samantha K. Wheller"'
Autor:
Francesca Ingegnoli, Mauro Perretti, Egle Solito, Mark C. Blades, Samantha K. Wheller, Costantino Pitzalis
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
The effect of the glucocorticoid inducible protein annexin 1 (ANXA1) on the process of monocytic cell migration was studied using transfected U937 cells expressing variable protein levels. An antisense (AS) (36.4AS; ∼50% less ANXA1) and a sense (S)
Autor:
Mauro Perretti, Samantha K. Wheller, Costantino Pitzalis, Smaira Wahid, Mark C. Blades, A Manzo, Gabriel S. Panayi, Francesca Ingegnoli
Publikováno v:
Arthritis & Rheumatism. 46:824-836
Objective The mechanisms by which monocyte/macrophage cells migrate to the joint involve a series of integrated adhesion and signaling events in which chemokines and their receptors are strongly implicated. This study was undertaken to investigate th
Autor:
Mauro Perretti, Samantha K. Wheller
Publikováno v:
European Journal of Pharmacology. 331:65-71
Intercellular adhesion molecule-1 (ICAM-1) expression on three endothelial cell lines was differently modulated by pro-inflammatory cytokines, such as interleukin-1beta and tumour necrosis factor-alpha (TNF-alpha) and the glucocorticoid hormone dexam
Modulation of ICAM-1 Levels on U-937 Cells and Mouse Macrophages by Interleukin-1β and Dexamethasone
Publikováno v:
Biochemical and Biophysical Research Communications. 223:112-117
Differentiation of U-937 cells with phorbol ester (10 nM) induced a time-dependent (24 h or 48 h) increase of adhesion molecules and lipocortin 1 expression on the cell surface. Stimulation with interleukin-1 beta for a further 16 h increased the lev
Publikováno v:
Biochemical Pharmacology. 50:1037-1042
A multi-faceted approach was used to investigate the effect of an anti-inflammatory peptide derived from human lipocortin 1 N-terminus region (amino acid 2–26; termed human Ac2–26) on human neutrophil activation in vitro . When incubated with pur
Autor:
Ivana Aiello, Helen C. Christian, K.G. Mugridge, Mauro Perretti, Samantha K. Wheller, John F. Morris, Roderick J. Flower, N. J. Goulding
Publikováno v:
Cell biology international. 24(3)
Annexin I, a member of the calcium- and phospholipid-binding annexin superfamily of proteins, is largely present in human neutrophils. To determine its exact intracellular distribution a combination of flow cytometry, confocal microscopy and electron
Autor:
Mauro Perretti, Roderick J. Flower, Nicolas J. Goulding, Samantha K. Wheller, Robert Hannon, Jamie D. Croxtall
Publikováno v:
Nature medicine. 2(11)
Polymorphonuclear leukocyte (PMN) migration into sites of inflammation is fundamental to the host defense response. Activation of endothelial cells and PMNs increases the expression or activation of adhesion molecules, culminating in rolling and subs
Autor:
Roderick J. Flower, Jeanette G. Harris, Amrita Ahluwalia, Mauro Perretti, Samantha K. Wheller, Hayley J. Harris
1. An immuno-neutralization strategy was employed to investigate the role of endogenous lipocortin 1 (LC1) in acute inflammation in the mouse. 2. Mice were treated subcutaneously with phosphate-buffered solution (PBS), non-immune sheep serum (NSS) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f056dbef45d277be0d669aa7a172c1fa
https://europepmc.org/articles/PMC1909779/
https://europepmc.org/articles/PMC1909779/