Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha K. Teixeira"'
Autor:
Iguaracy Pinheiro-de-Sousa, Miriam H. Fonseca-Alaniz, Samantha K. Teixeira, Mariliza V. Rodrigues, Jose E. Krieger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Endothelial dysfunction (ED) is a hallmark of atherosclerosis and is influenced by well-defined risk factors, including hypoxia, dyslipidemia, inflammation, and oscillatory flow. However, the individual and combined contributions to the mole
Externí odkaz:
https://doaj.org/article/1b8061ba28d84be9959b685d8e22ba4c
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Three-dimensional protein structure is directly correlated with its function and its determination is critical to understanding biological processes and addressing human health and life science problems in general. Although new protein structures are
Externí odkaz:
https://doaj.org/article/223ae697af404cf7ac017898b15e8f8c
Autor:
Fernando P. N. Rossi, José S. L. Patané, Vinicius de Souza, Jennifer M. Neyra, Rogério S. Rosa, Jose E. Krieger, Samantha K. Teixeira
Genome-wide association studies (GWAS) and polygenic risk scores (PRS) are multistep analytical tools to identify genetic variants and to assess their contribution to phenotypes/diseases. These analyses are evolving and becoming instrumental to under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67752218a5f4b812167dc48d8380b2e8
https://doi.org/10.1101/2023.05.03.539305
https://doi.org/10.1101/2023.05.03.539305
Publikováno v:
Hypertension. 79
The heritability of arterial hypertension ranges from 25 to 68%, but the underlying genetic determinants remain elusive. Thousands of variants with small effects on systolic blood pressure (SBP) from European Ancestry Genome-Wide Association Studies
Autor:
Thiago Rentz, Caio de Assis Moura Tavares, Pamella Araujo Malagrino, Bruno Caramelli, José Eduardo Krieger, Adriana C. C. Girardi, Samantha K Teixeira, Acaris Benetti, Gabriel M D Pereira, F. Martins, Thiago Matheus Santos Rios
Publikováno v:
Bioscience Reports
The angiotensin-converting enzyme (ACE)/Angiotensin II (Ang II) and angiotensin-converting enzyme 2 (ACE2)/angiotensin-(1-7) (Ang-(1-7)) pathways are coexpressed in most tissues. The balance between these pathways determines, at least in part, whethe
Autor:
Miguel José Francisco Neto, José Eduardo Krieger, Iguaracy Pinheiro de Sousa, Glaucylara Reis Geovanini, Guilherme Ciconelli Del Guerra, Samantha K Teixeira, Alexandre C. Pereira, Luz Marina Gomez Gomez
Publikováno v:
International Journal of Cardiology. Hypertension, Vol 6, Iss, Pp 100043-(2020)
International Journal of Cardiology Hypertension
International Journal of Cardiology Hypertension
Background and aims Carotid intima-media thickness (cIMT) is a strong predictor of cardiovascular events and associated with metabolic syndrome (MetS). MetS is a cluster of cardiovascular risk factors, but the association structure between specific f
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Blood pressure regulation in humans has long been known to be a genetically determined trait. The identification of causal genetic modulators for this trait has been unfulfilling at the least. Despite the recent advances of genome-wide genetic studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b628b29b920186edfdd53d229a672c0
Autor:
Alexandre C. Pereira, Mariliza Velho Rodrigues, André Ramos Vaquero, José Eduardo Krieger, Samantha Vieira Omae, Noely Evangelista Ferreira, Samantha K Teixeira
Publikováno v:
Physiological Genomics. 44:903-914
The single nucleotide polymorphism (SNP) within the TCF7L2 gene, rs7903146, is, to date, the most significant genetic marker associated with Type 2 diabetes mellitus (T2DM) risk. Nonetheless, its functional role in disease pathology is poorly underst
Publikováno v:
The FASEB Journal. 27