Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha J. Paddock"'
Autor:
Michael A. Flinn, Santiago Alvarez-Argote, Makenna C. Knas, Victor Alencar Almeida, Samantha J. Paddock, Xiaoxu Zhou, Tyler Buddell, Ayana Jamal, Reiauna Taylor, Pengyuan Liu, Jenny Drnevich, Michaela Patterson, Brian A. Link, Caitlin C. O’Meara
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionWhile Yap and Wwtr1 regulate resident cardiac fibroblast to myofibroblast differentiation following cardiac injury, their role specifically in activated myofibroblasts remains unexplored.MethodsWe assessed the pathophysiological and cellu
Externí odkaz:
https://doaj.org/article/4d0c10948b0b424983e1bfaad5739a9c
Autor:
Michael A. Flinn, Santiago Alvarez-Argote, Makenna C. Knas, Victor Alencar Almeida, Samantha J. Paddock, Xiaoxu Zhou, Tyler Buddell, Ayana Jamal, Pengyuan Liu, Jenny Drnevich, Michaela Patterson, Brian A. Link, Caitlin C. O’Meara
While Yap and Wwtr1 regulate resident cardiac fibroblast to myofibroblast differentiation following cardiac injury, their role specifically in activated myofibroblasts remains unexplored. Here we assess the pathophysiological and cellular consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47370ef03c05371a1b28950a06db42b2
https://doi.org/10.1101/2022.12.01.518714
https://doi.org/10.1101/2022.12.01.518714
Autor:
Victor Alencar-Almeida, Samantha K Swift, Aria Kenarsary, Michael A. Flinn, Michaela Patterson, Caitlin C. O'Meara, Santiago Alvarez-Argote, Samantha J. Paddock
Publikováno v:
J Mol Cell Cardiol
Neonatal heart regeneration depends on proliferation of pre-existing cardiomyocytes, yet the mechanisms driving regeneration and cardiomyocyte proliferation are not comprehensively understood. We recently reported that the anti-inflammatory cytokine,
Autor:
Michael J. Flister, Tina C. Wan, Dylan J Wodsedalek, Aria Kenarsary, Caitlin C. O'Meara, John A. Auchampach, Shirng-Wern Tsaih, Samantha J. Paddock
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 316:H24-H34
There is great interest in identifying signaling mechanisms by which cardiomyocytes (CMs) can enter the cell cycle and promote endogenous cardiac repair. We have previously demonstrated that IL-13 stimulated cell cycle activity of neonatal CMs in vit
Publikováno v:
Circulation Research. 127
Introduction: Heart failure is a very important disease in the United States and worldwide, with a projected prevalence of 8 million by 2030. Current therapy partially decreases progression; however, mortality continues to be high, and progression to
Publikováno v:
Circulation Research. 127
Introduction: During the first week of life, neonatal mice are able to regenerate their hearts after injury with minimal scarring. Work from our lab demonstrates that IL13 signaling is required for neonatal heart regeneration, however multiple IL13 r
Publikováno v:
Am J Physiol Heart Circ Physiol
Myostatin (MSTN) is a transforming growth factor (TGF)-β superfamily member that acts as a negative regulator of muscle growth and may play a role in cardiac remodeling. We hypothesized that inhibition of activin type II receptors (ACTRII) to reduce
Publikováno v:
The FASEB Journal. 33
Autor:
Caitlin C. O'Meara, Samantha J. Paddock, Aria Kenarsary, Michael J. Flister, Dylan J Wodsedalek
Publikováno v:
The FASEB Journal. 32