Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Samantha J. Griffiths"'
Autor:
Kevin A Robertson, Wei Yuan Hsieh, Thorsten Forster, Mathieu Blanc, Hongjin Lu, Peter J Crick, Eylan Yutuc, Steven Watterson, Kimberly Martin, Samantha J Griffiths, Anton J Enright, Mami Yamamoto, Madapura M Pradeepa, Kimberly A Lennox, Mark A Behlke, Simon Talbot, Jürgen Haas, Lars Dölken, William J Griffiths, Yuqin Wang, Ana Angulo, Peter Ghazal
Publikováno v:
PLoS Biology, Vol 14, Iss 3, p e1002364 (2016)
In invertebrates, small interfering RNAs are at the vanguard of cell-autonomous antiviral immunity. In contrast, antiviral mechanisms initiated by interferon (IFN) signaling predominate in mammals. Whilst mammalian IFN-induced miRNA are known to inhi
Externí odkaz:
https://doaj.org/article/2a7e4b86c96d49edbfa01de93c137949
Autor:
Samantha J. Griffiths, Christine Burkard, George Goussetis, S.K. Pavuluri, Konstantinos Kossenas, Nico Bruns, Juergen Haas, Symon K. Podilchak, Robert J. Chadwick, Marc P.Y. Desmulliez, Davide Comite, Chao Guo, Pascual D. Hilario Re
Publikováno v:
Kossenas, K, Podilchak, S, Comite, D, Hilario Re, P D, Goussetis, G, Pavuluri, S K, Griffiths, S, Chadwick, R, Guo, C, Bruns, N, Tait-Burkard, C, Haas, J G & Desmulliez, M P Y 2021, ' A Methodology for Remote Microwave Sterilization Applicable to the Coronavirus and Other Pathogens using Retrodirective Antenna Arrays ', IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, pp. 1-12 . https://doi.org/10.1109/JERM.2021.3077110
This paper describes an innovative remote surface sterilization approach applicable to the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The process is based on the application of a liquid film on the surface or objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13655dc57b8538bd5d03636e38f9db3
https://hdl.handle.net/20.500.11820/3bb79527-36dc-4322-87ad-229d00fb7e5f
https://hdl.handle.net/20.500.11820/3bb79527-36dc-4322-87ad-229d00fb7e5f
Autor:
Philippa M Beard, Samantha J Griffiths, Orland Gonzalez, Ismar R Haga, Tali Pechenick Jowers, Danielle K Reynolds, Jan Wildenhain, Hille Tekotte, Manfred Auer, Mike Tyers, Peter Ghazal, Ralf Zimmer, Jürgen Haas
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98431 (2014)
Vaccinia virus (VACV) is a large, cytoplasmic, double-stranded DNA virus that requires complex interactions with host proteins in order to replicate. To explore these interactions a functional high throughput small interfering RNA (siRNA) screen targ
Externí odkaz:
https://doaj.org/article/54e0675f17ff4ff48133bcd1756b2464
Autor:
Lars Muhl, Viktoria Kalna, Christine Tait-Burkard, Christer Betsholtz, Urban Lendahl, Samantha J. Griffiths, Liqun He, Maarja Andaloussi-Mäe, Jürgen Haas, Nicky M. Craig, Michela Noseda, Andrew H. Baker, Graeme M. Birdsey, Anna M. Randi, Alik Huseynov, Ian R McCracken, Claire Peghaire, Sarah Fletcher, Alison Daniels, Gaye Saginc
Publikováno v:
Mccracken, I R, Saginc, G, He, L, Huseynov, A, Daniels, A, Fletcher, S, Peghaire, C, Kalna, V, Andaloussi-mäe, M, Muhl, L, Craig, N M, Griffiths, S J, Haas, J G, Tait-burkard, C, Lendahl, U, Birdsey, G M, Betsholtz, C, Noseda, M, Baker, A H & Randi, A M 2021, ' Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells ', Circulation . https://doi.org/10.1161/CIRCULATIONAHA.120.052824
McCracken, I, Saginc, G, He, L, Huseynov, A, Daniels, A, Fletcher, S, Peghaire, C, Kalna, V, Andaloussi-mäe, M, Muhl, L, Craig, N, Griffiths, S, Haas, J G, Tait-Burkard, C, Lendahl, U, Birdsey, G M, Betsholtz, C, Noseda, M, Baker, A H & Randi, AM 2021, ' Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cells ', Circulation, vol. 143, no. 8, pp. 865–868 . https://doi.org/10.1101/2020.12.02.391664, https://doi.org/10.1161/CIRCULATIONAHA.120.052824
McCracken, I, Saginc, G, He, L, Huseynov, A, Daniels, A, Fletcher, S, Peghaire, C, Kalna, V, Andaloussi-mäe, M, Muhl, L, Craig, N, Griffiths, S, Haas, J G, Tait-Burkard, C, Lendahl, U, Birdsey, G M, Betsholtz, C, Noseda, M, Baker, A H & Randi, AM 2021, ' Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cells ', Circulation, vol. 143, no. 8, pp. 865–868 . https://doi.org/10.1101/2020.12.02.391664, https://doi.org/10.1161/CIRCULATIONAHA.120.052824
A striking feature of severe COVID-19 is thrombosis in large as well as small vessels of multiple organs. This has led to the assumption that SARS-CoV-2 virus directly infects and damages the vascular endothelium. However, endothelial expression of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24aa94feee0c5342e43995e3943c7a0e
https://hdl.handle.net/20.500.11820/3bc7226a-64ab-47ee-a209-60b325542bf6
https://hdl.handle.net/20.500.11820/3bc7226a-64ab-47ee-a209-60b325542bf6
Autor:
Sarah Fletcher, Michela Noseda, Gaye Saginc, Christine Tait-Burkard, Claire Peghaire, Maarja Andaloussi-Mäe, Ian R McCracken, Alik Huseynov, Graeme M. Birdsey, Urban Lendahl, Alison Daniels, Andy Baker, Liqun He, Samantha J. Griffiths, Jürgen Haas, Nicky M. Craig, Anna M. Randi, Christer Betsholtz, Viktoria Kalna, Lars Muhl
Publikováno v:
Circulation
Autor:
Samantha J Griffiths, Manfred Koegl, Chris Boutell, Helen L Zenner, Colin M Crump, Francesca Pica, Orland Gonzalez, Caroline C Friedel, Gerald Barry, Kim Martin, Marie H Craigon, Rui Chen, Lakshmi N Kaza, Even Fossum, John K Fazakerley, Stacey Efstathiou, Antonio Volpi, Ralf Zimmer, Peter Ghazal, Jürgen Haas
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003514 (2013)
Herpes simplex virus type 1 (HSV-1) is a neurotropic virus causing vesicular oral or genital skin lesions, meningitis and other diseases particularly harmful in immunocompromised individuals. To comprehensively investigate the complex interaction bet
Externí odkaz:
https://doaj.org/article/c1319d0c08484c8a870675e878702559
Autor:
Juergen Haas, Nhan T. Pham, Paul Digard, Chen-Hsuin Lee, Samantha J. Griffiths, Manfred Auer, Finn Grey
Publikováno v:
mBio
mBio, Vol 10, Iss 5 (2019)
Lee, A, Griffiths, S, Digard, P, Pham, N, Auer, M, Haas, J & Grey, F 2019, ' Asparagine deprivation causes a reversible inhibition of Human Cytomegalovirus acute virus replication ', mBio, vol. 10, no. 5, e01651-19 . https://doi.org/10.1128/mBio.01651-19
mBio, Vol 10, Iss 5, p e01651-19 (2019)
mBio, Vol 10, Iss 5 (2019)
Lee, A, Griffiths, S, Digard, P, Pham, N, Auer, M, Haas, J & Grey, F 2019, ' Asparagine deprivation causes a reversible inhibition of Human Cytomegalovirus acute virus replication ', mBio, vol. 10, no. 5, e01651-19 . https://doi.org/10.1128/mBio.01651-19
mBio, Vol 10, Iss 5, p e01651-19 (2019)
HCMV accounts for more than 60% of complications associated with solid organ transplant patients. Prophylactic or preventative treatment with antivirals, such as ganciclovir, reduces the occurrence of early onset HCMV disease. However, late onset dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69339fbec6a9b25b9da731d6d89ccf0
https://doi.org/10.1101/690016
https://doi.org/10.1101/690016
Autor:
Finn Grey, Samantha J. Griffiths, Nhan T. Pham, Paul Digard, Chen-Hsuin Lee, Manfred Auer, Juergen Haas
Publikováno v:
Access Microbiology. 1
As an obligate intracellular parasite, human cytomegalovirus (HCMV) completely relies on host machinery to replicate. Understanding which host factors are required for virus replication contributes to our understanding of virus biology and cell biolo
Publikováno v:
Journal of Innate Immunity
Since its discovery in 2003, the type III interferon-λ (IFN-λ) family has been found to contribute significantly to the host response to infection. Whilst IFN-λ shares many features with type I IFN induction and signalling pathways, the tissue-spe
Publikováno v:
Journal of Virology
Haga, I R, Pechenick Jowers, T, Griffiths, S J, Haas, J & Beard, P M 2014, ' TRAF2 facilitates Vaccinia virus replication by promoting rapid virus entry. ', Journal of Virology, vol. 88, no. 7, pp. 3664-3677 . https://doi.org/10.1128/JVI.03013-13
Haga, I R, Pechenick Jowers, T, Griffiths, S J, Haas, J & Beard, P M 2014, ' TRAF2 facilitates Vaccinia virus replication by promoting rapid virus entry. ', Journal of Virology, vol. 88, no. 7, pp. 3664-3677 . https://doi.org/10.1128/JVI.03013-13
Tumor necrosis factor receptor (TNFR)-associated factor 2 (TRAF2) is a pivotal intracellular mediator of signaling pathways downstream of TNFR1 and -2 with known pro- and antiviral effects. We investigated its role in the replication of the prototype