Zobrazeno 1 - 6
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pro vyhledávání: '"Samantha J. Fromme"'
Autor:
Samantha J. Fromme, Robert H. Cox
Publikováno v:
Cell Biochemistry and Biophysics. 74:499-511
We have shown that three components contribute to functional voltage gated K+ (K v) currents in rat small mesenteric artery myocytes: (1) Kv1.2 plus Kv1.5 with Kvβ1.2 subunits, (2) Kv2.1 probably associated with Kv9.3 subunits, and (3) Kv7.4 subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797b58483f37905e6875b94fb65b7ddb
https://doi.org/10.1007/s12013-016-0763-4
https://doi.org/10.1007/s12013-016-0763-4
Autor:
Robert H. Cox, Samantha J. Fromme
Publikováno v:
Cell Biochemistry and Biophysics. 74:263-276
Multiple K v channel complexes contribute to total K v current in numerous cell types and usually subserve different physiological functions. Identifying the complete compliment of functional K v channel subunits in cells is a prerequisite to underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c751588ded261e7286ca08ef0d5c7c
https://doi.org/10.1007/s12013-015-0715-4
https://doi.org/10.1007/s12013-015-0715-4
Autor:
Samantha J. Fromme, Robert H. Cox
Publikováno v:
American Journal of Hypertension. 28:1229-1239
Background Enhanced function of dihydropyridine-sensitive Ca2+ channels (CaV) in hypertensive arterial myocytes (HAM) is well accepted. Increased protein expression of pore forming α1-subunits contributes to this effect, but cannot explain all of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d527598be3ed106c180baf96dc3172e
https://doi.org/10.1093/ajh/hpv024
https://doi.org/10.1093/ajh/hpv024
Autor:
Samantha J. Fromme, Robert H. Cox
Publikováno v:
American Journal of Physiology-Cell Physiology. 305:C896-C905
Alternative splicing of the voltage-gated Ca2+(CaV) α1-subunit adds to the functional diversity of Ca2+channels. A variant with a 73-nt deletion in exon 15 of the Cav1.2 α1-subunit (Cav1.2Δ73) produced by alternative splicing that predicts a trunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e5abc955990848f4af566e6e1e12a2
https://doi.org/10.1152/ajpcell.00217.2013
https://doi.org/10.1152/ajpcell.00217.2013
Autor:
Donglin Guo, Peter R. Kowey, Yaxun Sun, Xiao-Qing Quan, Robert H. Cox, Gan-Xin Yan, Li Zhang, Chinmay Patel, Ping Zhang, Jihong Guo, Samantha J. Fromme
Publikováno v:
Journal of molecular and cellular cardiology. 50(3)
A gain of function mutation N588K in the KCNH2 gene that encodes HERG channels has been shown to underlie the SQT1 form of short QT syndrome (SQTS). We describe a different mutation in the KCNH2 gene in a Chinese family with clinical evidence of SQTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090219d0fde0bcb5c381732797687037
https://pubmed.ncbi.nlm.nih.gov/21130771
https://pubmed.ncbi.nlm.nih.gov/21130771
Publikováno v:
American journal of hypertension. 21(2)
Background We have previously demonstrated differences in the gene expression of voltage-gated K v1.X channel alpha-subunits in arteries from Wistar-Kyoto rats (WKYs) and spontaneously hypertensive rats (SHRs). The purpose of this study was to test t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5919982bdb591e003000ac376b13d4a
https://pubmed.ncbi.nlm.nih.gov/18174882
https://pubmed.ncbi.nlm.nih.gov/18174882