Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha J Owens"'
Autor:
Tertia D Purves-Tyson, Samantha J Owens, Kay L Double, Reena Desai, David J Handelsman, Cynthia Shannon Weickert
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91151 (2014)
Adolescent males have an increased risk of developing schizophrenia, implicating testosterone in the precipitation of dopamine-related psychopathology. Evidence from adult rodent brain indicates that testosterone can modulate nigrostriatal dopamine.
Externí odkaz:
https://doaj.org/article/0aedeec00a99490f8a0a7b6f39096e3a
Autor:
Yunting Zhu, Samantha J. Owens, Caitlin E. Murphy, Kachikwulu Ajulu, Debora Rothmond, Tertia Purves-Tyson, Frank Middleton, Maree J. Webster, Cynthia Shannon Weickert
Publikováno v:
Brain, Behavior, and Immunity. 105:149-159
Dopamine dysregulation in schizophrenia may be associated with midbrain inflammation. Previously, we found elevated levels of pro-inflammatory cytokine mRNAs in the post-mortem midbrain of people with schizophrenia (46%) but not from unaffected contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8965f2f202eefa1f972e5f6c0523b2
https://doi.org/10.1016/j.bbi.2022.06.012
https://doi.org/10.1016/j.bbi.2022.06.012
Publikováno v:
Psychiatry research. 280
Anxiety and depressive disorders are more prevalent in hypogonadal men. Low testosterone levels are associated with greater negative symptoms and impaired cognition in men with schizophrenia. Thus, androgens may contribute to brain pathophysiology in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfac7f0d727ada2497cb7fcfc186c30c
https://pubmed.ncbi.nlm.nih.gov/31446215
https://pubmed.ncbi.nlm.nih.gov/31446215
Publikováno v:
Biological Psychiatry. 85:S280-S281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bc98eb2f468074be7a05e26aefbe7f
https://doi.org/10.1016/j.biopsych.2019.03.711
https://doi.org/10.1016/j.biopsych.2019.03.711
Autor:
Tertia D. Purves-Tyson, C. Shannon Weickert, Caitlin E. Murphy, Thomas W. Weickert, Samantha J Owens
Publikováno v:
Journal of Neuroendocrinology. 30:e12538
Schizophrenia is a disabling illness that is typically first diagnosed during late adolescence to early adulthood. It has an unremitting course and is often treatment-resistant. Many clinical aspects of the illness suggest that sex steroid-nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f6beec19ba6a14e8caff8ba24158b8
https://doi.org/10.1111/jne.12538
https://doi.org/10.1111/jne.12538
Autor:
Glenda M. Halliday, Samantha J Owens, T. McCrossin, Kay L. Double, Tertia D. Purves-Tyson, Debora A. Rothmond, C. Shannon Weickert, Julia Stevens
Publikováno v:
Translational Psychiatry
The dopamine hypothesis of schizophrenia posits that increased subcortical dopamine underpins psychosis. In vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4cb91325a83130e42cdf04146086ea
https://doi.org/10.1038/tp.2016.257
https://doi.org/10.1038/tp.2016.257
Autor:
Reena Desai, Kay L. Double, Samantha J Owens, David J. Handelsman, Tertia D. Purves-Tyson, Cynthia Shannon Weickert
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e91151 (2014)
PLoS ONE, Vol 9, Iss 3, p e91151 (2014)
Adolescent males have an increased risk of developing schizophrenia, implicating testosterone in the precipitation of dopamine-related psychopathology. Evidence from adult rodent brain indicates that testosterone can modulate nigrostriatal dopamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d972583263c6fafda59c0bd0928328
https://pubmed.ncbi.nlm.nih.gov/24618531
https://pubmed.ncbi.nlm.nih.gov/24618531
Autor:
Cynthia Shannon Weickert, David J. Handelsman, Sonia Bustamante, Samantha J Owens, Tertia D. Purves-Tyson, Kay L. Double
Publikováno v:
BMC Neuroscience, Vol 13, Iss 1, p 95 (2012)
BMC Neuroscience
BMC Neuroscience
Background Increased risk of schizophrenia in adolescent males indicates that a link between the development of dopamine-related psychopathology and testosterone-driven brain changes may exist. However, contradictions as to whether testosterone incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c681a8445e621ac7a587aa8f4b3b1001
http://www.biomedcentral.com/1471-2202/13/95
http://www.biomedcentral.com/1471-2202/13/95
Autor:
Tertia D. Purves-Tyson, Kate Robinson, Amelia M. Brown, Danny Boerrigter, Helen Q. Cai, Christin Weissleder, Samantha J. Owens, Debora A. Rothmond, Cynthia Shannon Weickert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Increased cytokine and inflammatory-related transcripts are found in the ventral midbrain, a dopamine neuron-rich region associated with schizophrenia symptoms. In fact, half of schizophrenia cases can be defined as having a “high inflammatory/immu
Externí odkaz:
https://doaj.org/article/469da861d99b486b90ec11e5fa7102fc