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pro vyhledávání: '"Samantha I. Liang"'
Autor:
Samantha I. Liang, Bettina van Lengerich, Kelsie Eichel, Minkwon Cha, David M. Patterson, Tae-Young Yoon, Mark von Zastrow, Natalia Jura, Zev J. Gartner
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Summary: Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether specific receptor conformations and olig
Externí odkaz:
https://doaj.org/article/280c94300e0942188e4040eef907c2e2
Autor:
Connor P. Healy, Johanna M. Sweere, Samantha I. Liang, Natalia Sigal, Elizabeth Enrico, Li-Chun Cheng, Anastasia Lucas, Marshall A. Thompson, Diane M. Da Silva, Justin A. Jarrell, Ramji Srinivasan, Matthew H. Spitzer, Ngan Nguyen, Christine N. Spencer
Publikováno v:
Cancer Research. 83:2138-2138
Checkpoint immunotherapies (CPI) have resulted in long lasting clinical responses; however, CPI treatment comes with the risk of immune-related adverse events (irAEs). Previous reports have established a correlation between irAE occurrence and better
Autor:
Bettina van Lengerich, Mark von Zastrow, David M. Patterson, Minkwon Cha, Natalia Jura, Tae-Young Yoon, Kelsie Eichel, Zev J. Gartner, Samantha I. Liang
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Cell reports, vol 22, iss 10
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Cell reports, vol 22, iss 10
Summary Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether specific receptor conformations and oligo
Publikováno v:
Journal of the American Chemical Society
Expansion of antibody scaffold diversity has the potential to expand the neutralizing capacity of the immune system and to generate enhanced therapeutics and probes. Systematic exploration of scaffold diversity could be facilitated with a modular and
Publikováno v:
Biomacromolecules
Lipid modifications provide efficient targeting of oligonucleotides to live cell membranes in a range of applications. Targeting efficiency is a function of the rate of lipid DNA insertion into the cell surface and its persistence over time. Here we