Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Samantha G.L. Keyser"'
Autor:
Maksim V. Baranov, Frans Bianchi, Anastasiya Schirmacher, Melissa A.C. van Aart, Sjors Maassen, Elke M. Muntjewerff, Ilse Dingjan, Martin ter Beest, Martijn Verdoes, Samantha G.L. Keyser, Carolyn R. Bertozzi, Ulf Diederichsen, Geert van den Bogaart
Publikováno v:
iScience, Vol 11, Iss , Pp 160-177 (2019)
Summary: Antigen presentation to T cells in major histocompatibility complex class II (MHC class II) requires the conversion of early endo/phagosomes into lysosomes by a process called maturation. Maturation is driven by the phosphoinositide kinase P
Externí odkaz:
https://doaj.org/article/777bcaf6cb384f6589d631ee7045013c
Autor:
Kerwyn Casey Huang, Christopher Ealand, Bavesh D. Kana, C.J. Cambier, Samantha G.L. Keyser, Green Ahn, Benjamin D. Knapp, Carolyn R. Bertozzi, Ashley Utz, Mireille Kamariza, Teresia Chen
Publikováno v:
JACS Au, Vol 1, Iss 9, Pp 1368-1379 (2021)
JACS Au
JACS Au
There is an urgent need for point-of-care tuberculosis (TB) diagnostic methods that are fast, inexpensive, and operationally simple. Here, we report on a bright solvatochromic dye trehalose conjugate that specifically detects Mycobacterium tuberculos
Autor:
Elke M. Muntjewerff, Anastasiya Schirmacher, Sjors Maassen, Martijn Verdoes, Samantha G.L. Keyser, Martin ter Beest, Maksim V. Baranov, Frans Bianchi, Ilse Dingjan, Ulf Diederichsen, Melissa A.C. van Aart, Geert van den Bogaart, Carolyn R. Bertozzi
Publikováno v:
iScience, 11, 160-177. Elsevier
iScience, 11, 160-177
iScience, 11, pp. 160-177
iScience
iScience, Vol 11, Iss, Pp 160-177 (2019)
iScience, 11, 160-177
iScience, 11, pp. 160-177
iScience
iScience, Vol 11, Iss, Pp 160-177 (2019)
Summary Antigen presentation to T cells in major histocompatibility complex class II (MHC class II) requires the conversion of early endo/phagosomes into lysosomes by a process called maturation. Maturation is driven by the phosphoinositide kinase PI
Publikováno v:
The Journal of Organic Chemistry. 83:7467-7479
Site-selective protein modification based on covalent reactions of peptide tags and small molecules is a key capability for basic research as well as for the development of new therapeutic bioconjugates. Here, we describe the computation-guided ratio
Publikováno v:
Journal of the American Chemical Society. 138:7040-7047
High-throughput enzyme activity screens are essential for target characterization and drug development, but few assays employ techniques or reagents that are applicable to both in vitro and live cell settings. Here, we present a class of selective an
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:1094-1097
Protein sumoylation is a dynamic posttranslational modification involved in diverse biological processes during cellular homeostasis and development. Recently sumoylation has been shown to play a critical role in cancer, although to date there are fe
Publikováno v:
Chemistry & Biology. (4):604-613
The dynamic, posttranslational modification of proteins with a SUMO tag has been recognized as an important cellular regulatory mechanism relevant to a number of cancers as well as normal embryonic development. As part of a program aimed towards the