Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Samantha E. Wilner"'
Publikováno v:
Aging Cell
Genomic instability is one of the hallmarks of aging, and both DNA damage and mutations have been found to accumulate with age in different species. Certain gene families, such as sirtuins and the FoxO family of transcription factors, have been shown
Autor:
Samantha E Wilner, Brian Wengerter, Keith Maier, Maria de Lourdes Borba Magalhães, David Soriano Del Amo, Supriya Pai, Felipe Opazo, Silvio O Rizzoli, Amy Yan, Matthew Levy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin recep
Externí odkaz:
https://doaj.org/article/f49eee81e2054e35bc941fe8c69cbbd6
Autor:
Qi Xiao, Samuel E. Sherman, Tobias Baumgart, Samantha E. Wilner, Zachary T. Graber, Virgil Percec
Publikováno v:
Langmuir. 34:5527-5534
Lamellar to nonlamellar membrane shape transitions play essential roles in key cellular processes, such as membrane fusion and fission, and occur in response to external stimuli, including drug treatment and heat. A subset of these transitions can be
Autor:
Eben Alsberg, Mathew Levy, Keith E. Maier, Cong Truc Huynh, Samantha E. Wilner, Alex Gilewski, Nicholas Kwon, Minh Khanh Nguyen
Publikováno v:
Science Advances
Covalently tethering RNA to hydrogel provides the prolonged presentation of RNA for locally sustained cellular gene silencing.
Small interfering RNA (siRNA) has found many applications in tissue regeneration and disease therapeutics. Effective a
Small interfering RNA (siRNA) has found many applications in tissue regeneration and disease therapeutics. Effective a
Autor:
Michael L. Klein, Christopher J. Wilson, Nina Yu. Kostina, Khosrow Rahimi, Shangda Li, Qi Xiao, Tobias Baumgart, Hong Han, Virgil Percec, Daniela A. Wilson, Irene Buzzacchera, Cesar Rodriguez-Emmenegger, Martin Möller, B. Jelle Toebes, Samantha E. Wilner
Publikováno v:
Biomacromolecules, 20, 2, pp. 712-727
Biomacromolecules 20(2), 712-727 (2019). doi:10.1021/acs.biomac.8b01405 special issue: "Special issue: The Rational Design of Multifunctional Renewable-Resourced Materials"
1. Symposium on Rational Design of Multifunctional Renewable-Resourced Materials, Boston, MA, USA, 2018-08-19-2018-08-23
Biomacromolecules, 20, 712-727
Biomacromolecules
Biomacromolecules 20(2), 712-727 (2019). doi:10.1021/acs.biomac.8b01405 special issue: "Special issue: The Rational Design of Multifunctional Renewable-Resourced Materials"
1. Symposium on Rational Design of Multifunctional Renewable-Resourced Materials, Boston, MA, USA, 2018-08-19-2018-08-23
Biomacromolecules, 20, 712-727
Biomacromolecules
1st Symposium on Rational Design of Multifunctional Renewable-Resourced Materials, Boston, MA, USA, 19 Aug 2018 - 23 Aug 2018; Biomacromolecules 20(2), 712-727 (2019). doi:10.1021/acs.biomac.8b01405 special issue: "Special issue: The Rational Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7fc1b81646da3bcc50ccbb2987d17f
https://hdl.handle.net/2066/201525
https://hdl.handle.net/2066/201525
Autor:
Michael L. Klein, Qi Xiao, Paul A. Heiney, Srujana S. Yadavalli, Sergei A. Vinogradov, Mark Goulian, Daniel A. Hammer, Ellen H. Reed, Tobias Baumgart, Jack D. Rubien, Samantha E. Wilner, Dipankar Sahoo, Virgil Percec, Zhichun Wang
Publikováno v:
Journal of the American Chemical Society. 138:12655-12663
The modular synthesis of a library containing seven self-assembling amphiphilic Janus dendrimers is reported. Three of these molecules contain environmentally friendly chiral-racemic fluorinated dendrons in their hydrophobic part (RF), one contains a
Autor:
Keith E. Maier, Deborah Palliser, Gayatri Mukherjee, Samantha E. Wilner, Joseph A. Katakowski, Michael Travis Harrison, Matthew Levy, Teresa P. DiLorenzo
Publikováno v:
Molecular Therapy
Due to their ability to knock down the expression of any gene, siRNAs have been heralded as ideal candidates for treating a wide variety of diseases, including those involving "undruggable" targets. However, the therapeutic potential of siRNAs remain
Autor:
Samuel E. Sherman, Daniel A. Hammer, Michael L. Klein, Tobias Baumgart, Virgil Percec, Qi Xiao, Samantha E. Wilner, Cody Dazen, Xuhao Zhou, Ellen H. Reed, Wataru Shinoda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(34)
A three-component system of Janus dendrimers (JDs) including hydrogenated, fluorinated, and hybrid hydrogenated–fluorinated JDs are reported to coassemble by film hydration at specific ratios into an unprecedented class of supramolecular Janus part
Publikováno v:
Biophysical Journal. 114:272a-273a
Autor:
Matthew Levy, Samantha E. Wilner
Publikováno v:
Methods in Molecular Biology ISBN: 9781493931965
Aptamers selected against cell surface receptors represent a unique set of ligands that can be used to target nanoparticles and other therapeutics to specific cell types. Here, we describe a method for using aptamers to deliver stable nucleic acid li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1ef86ccecee0811cbc58726c6b4cf9
https://doi.org/10.1007/978-1-4939-3197-2_18
https://doi.org/10.1007/978-1-4939-3197-2_18