Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Samantha Del Borrello"'
Autor:
Margot J Lautens, June H Tan, Xènia Serrat, Samantha Del Borrello, Michael R Schertzberg, Andrew G Fraser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009991 (2021)
Soil transmitted helminths (STHs) are major human pathogens that infect over a billion people. Resistance to current anthelmintics is rising and new drugs are needed. Here we combine multiple approaches to find druggable targets in the anaerobic meta
Externí odkaz:
https://doaj.org/article/4c6646960b5242a4b5fbec3f2473cff7
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 9, Pp 2941-2952 (2018)
Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of
Externí odkaz:
https://doaj.org/article/d21517de8b634a8b8ba2e05b1a7afcf0
Autor:
Samantha Del Borrello, Margot Lautens, Kathleen Dolan, June H Tan, Taylor Davie, Michael R Schertzberg, Mark A Spensley, Amy A Caudy, Andrew G Fraser
Publikováno v:
eLife, Vol 8 (2019)
Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal speci
Externí odkaz:
https://doaj.org/article/93eba85e4d274af2abe43dd09b991931
Autor:
Margot Lautens, Serrat X, Andrew G. Fraser, June H. Tan, Samantha Del Borrello, Michael R Schertzberg
Soil transmitted helminths (STHs) are major human pathogens that infect over a billion people. Resistance to current anthelmintics is rising and new drugs are needed. Here we combine multiple approaches to find druggable targets that are essential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af3848c98be5a71c84201a14dce1b5b
https://doi.org/10.1101/2021.03.24.436840
https://doi.org/10.1101/2021.03.24.436840
Autor:
Amy A. Caudy, Andrew G. Fraser, Mark Spensley, June H. Tan, Kathleen Dolan, Michael R Schertzberg, Samantha Del Borrello, Taylor Davie, Margot Lautens
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685609291759f04f6939bdfe7660dfee
https://doi.org/10.7554/elife.48165
https://doi.org/10.7554/elife.48165
Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::934c799d41ee3a64582bb21c97e11f33
https://doi.org/10.1101/299719
https://doi.org/10.1101/299719