Heterogeneous side effects of cortical inactivation in behaving animals

Autor: Xiaoqin Liu, Samantha Debes, Valentin Dragoi, Roger Janz, John L. Spudich, Ariana R. Andrei, Mircea I. Chelaru, Elsa M. Rodarte

Publikováno v: eLife, Vol 10 (2021)

Cortical inactivation represents a key causal manipulation allowing the study of cortical circuits and their impact on behavior. A key assumption in inactivation studies is that the neurons in the target area become silent while the surrounding corti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511459b5535469712232db8f5d1bae28
https://doi.org/10.7554/elife.66400

An Open Resource for Non-human Primate Optogenetics

Autor: Wolfram Schultz, Marc Alwin Gieselmann, Giacomo Benvenuti, Daniel L. Albaugh, Masahiko Takada, Christopher I. Petkov, Azadeh Yazdan-Shahmorad, Mark A.G. Eldridge, Francesco Fabbrini, Roberto Calcedo, Krishna V. Shenoy, Karl Deisseroth, Leah Acker, Naotaka Fujii, Spencer C Chen, Masayuki Matsumoto, Adam Kohn, Eyal Seidemann, Adriana Galván, Janina Hüer, Samantha Debes, Eghbal A. Hosseini, Selina S. Solomon, Haoran Xu, Philip N. Sabes, Xing Hu, Caitlin R. Siu, James Cavanaugh, Hidetoshi Amita, Seth W. Egger, Arash Afraz, Yuzhi Chen, Diego Mendoza-Halliday, Ken-ichi Inoue, Evan D. Remington, Thomas Wichmann, Wim Vanduffel, Niansheng Ju, Christopher R. Fetsch, Michael Ortiz-Rios, Sorin Pojoga, Michele A. Basso, Carsten Klein, Hala G. El-Nahal, Roberto A. Gulli, Robert H. Wurtz, Rundong Jiang, John L. Spudich, Yoland Smith, Charu Ramakrishnan, Ji Dai, Supriya Ghosh, Yann Suhan Senova, Alexander Thiele, John H. R. Maunsell, Matthew P. Whitmire, Frederick Federer, David L. Sheinberg, Kazutaka Maeda, Robert Desimone, Mehrdad Jazayeri, Marc A. Sommer, Sébastien Tremblay, Michael C. Schmid, Shiming Tang, Kohitij Kar, Rishi Rajalingham, Andrew M. Clark, Okihide Hikosaka, Michael J. Caiola, Michal G. Fortuna, Ross S. Muers, Richard C. Saunders, Alexander Gail, Hansjörg Scherberger, Stéphane Palfi, Roger Janz, Michael N. Shadlen, Robert M. Friedman, Puiu F. Balan, Cambria Revsine, William R. Stauffer, Misako Komatsu, Ilya E. Monosov, Martin O. Bohlen, Stefan Treue, Lauri Nurminen, Michael L. Platt, Alessandra Angelucci, Mykyta M. Chernov, James J. DiCarlo, Daniel J. O’Shea, Anna W. Roe, Rufin Vogels, Julio Martinez-Trujillo, Valentin Dragoi, Amir Aschner, Ariana R. Andrei

Publikováno v: Neuron
Physiology and Pharmacology Publications

Optogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed. To make evidence-based decisions in primate optogenetics, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b1acc1259f0ac65a1d2c45be564151
https://doi.org/10.1016/j.neuron.2020.09.027