Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Samantha Cialfi"'
Autor:
Maria Pelullo, Sabrina Zema, Mariangela De Carolis, Samantha Cialfi, Maria Valeria Giuli, Rocco Palermo, Carlo Capalbo, Giuseppe Giannini, Isabella Screpanti, Saula Checquolo, Diana Bellavia
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Colorectal cancer (CRC) is characterized by early metastasis, resistance to anti-cancer therapy, and high mortality rate. Despite considerable progress in the development of new treatment options that improved survival benefits in patients with early
Externí odkaz:
https://doaj.org/article/5a75d1d611384d85bb357cc8053ec92e
Autor:
Carlo De Blasio, Nagendra Verma, Marta Moretti, Samantha Cialfi, Azzurra Zonfrilli, Matteo Franchitto, Federica Truglio, Enrico De Smaele, Hidenori Ichijo, Isao Naguro, Isabella Screpanti, Claudio Talora
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Both CDKN1A (p21 Waf1/Cip1) and Apoptosis signal-regulating kinase 1 (ASK1) play important roles in tumorigenesis. The role of p21 Waf1/Cip1 in attenuating ASK1-induced apoptosis by various stress conditions is well established. However, how
Externí odkaz:
https://doaj.org/article/cd3c8cd4d2384a64b4db6cc4a373c486
Autor:
Martina Del Gaizo, Ilaria Sergio, Sara Lazzari, Samantha Cialfi, Maria Pelullo, Isabella Screpanti, Maria Pia Felli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 829 (2022)
Acute lymphoblastic leukaemia (ALL) is an aggressive haematological tumour driven by the malignant transformation and expansion of B-cell (B-ALL) or T-cell (T-ALL) progenitors. The evolution of T-ALL pathogenesis encompasses different master developm
Externí odkaz:
https://doaj.org/article/fb9573cbecd0466c81eb2e42d6fe1a49
Autor:
Maria Pelullo, Roberta Quaranta, Claudio Talora, Saula Checquolo, Samantha Cialfi, Maria Pia Felli, Geertruy te Kronnie, Chiara Borga, Zein Mersini Besharat, Rocco Palermo, Lucia Di Marcotullio, Anthony J. Capobianco, Alberto Gulino, Isabella Screpanti, Diana Bellavia
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 12, Pp 1007-1017 (2014)
Deregulated Notch signaling has been extensively linked to T-cell acute lymphoblastic leukemia (T-ALL). Here, we show a direct relationship between Notch3 receptor and Jagged1 ligand in human cell lines and in a mouse model of T-ALL. We provide evide
Externí odkaz:
https://doaj.org/article/d356072dca514796ae10aa4e773fcc16
Autor:
Nagendra Verma, Matteo Franchitto, Azzurra Zonfrilli, Samantha Cialfi, Rocco Palermo, Claudio Talora
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1073 (2019)
DNA is an entity shielded by mechanisms that maintain genomic stability and are essential for living cells; however, DNA is constantly subject to assaults from the environment throughout the cellular life span, making the genome susceptible to mutati
Externí odkaz:
https://doaj.org/article/68ae30da3bb743898d8ad454cf6df50a
Autor:
Sara Cattelani, Giovanna Ferrari-Amorotti, Sara Galavotti, Raffaella Defferrari, Barbara Tanno, Samantha Cialfi, Jenny Vergalli, Valentina Fragliasso, Clara Guerzoni, Gloria Manzotti, Angela Rachele Soliera, Chiara Menin, Roberta Bertorelle, Heather P. McDowell, Alessandro Inserra, Maria Luisa Belli, Luigi Varesio, Deborah Tweddle, Gian Paolo Tonini, Pierluigi Altavista, Carlo Dominici, Giuseppe Raschellà, Bruno Calabretta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 7, Pp 634-643 (2012)
The p53 gene is rarely mutated in neuroblastoma, but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. We investigated whether this polymorphism affects neuroblastoma risk and disease out
Externí odkaz:
https://doaj.org/article/a82fdf1e4a494fedb36b4d5a5686f82e
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1814 (2018)
The term orthodisease defines human disorders in which the pathogenic gene has orthologs in model organism genomes. Yeasts have been instrumental for gaining insights into the molecular basis of many human disorders, particularly those resulting from
Externí odkaz:
https://doaj.org/article/27a836d5a30144c6a26514b6deaec84b
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32047 (2012)
A growing body of evidence indicates that protein factors controlling translation play an important role in tumorigenesis. The protein known as eIF6 is a ribosome anti-association factor that has been implicated in translational initiation and in rib
Externí odkaz:
https://doaj.org/article/c9d5f0e1d7db4d2b83854d560c44b21d
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26601 (2011)
microRNAs (miRNAs) are a class of regulatory small non-coding molecules that control gene expression at post-transcriptional level. Deregulation of miRNA functions affects a variety of biological processes also involved in the etiology of several hum
Externí odkaz:
https://doaj.org/article/fa5e5f4240fe4011a129e0e6aed24ecf
Autor:
Azzurra Zonfrilli, Federica Truglio, Alessandra Simeone, Maria Pelullo, Valeria De Turris, Dario Benelli, Saula Checquolo, Diana Bellavia, Rocco Palermo, Daniela Uccelletti, Isabella Screpanti, Samantha Cialfi, Claudio Talora
Publikováno v:
Experimental Dermatology.