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pro vyhledávání: '"Samantha C. Hatfield"'
Autor:
Qiang Xiao, Zachary B. Jones, Samantha C. Hatfield, Dallin S. Ashton, Nicholas A. Dalley, Cody D. Dyer, Judah L. Evangelista, Joshua L. Price
Publikováno v:
RSC Chemical Biology. 3:1096-1104
Here we identify key criteria for designing PEG-stapled coiled coils with increased conformational and proteolytic stability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a7fa455b0095e3cf77dee1e0e3c42f
https://doi.org/10.1039/d1cb00237f
https://doi.org/10.1039/d1cb00237f
Autor:
Qiang, Xiao, Zachary B, Jones, Samantha C, Hatfield, Dallin S, Ashton, Nicholas A, Dalley, Cody D, Dyer, Judah L, Evangelista, Joshua L, Price
Publikováno v:
RSC chemical biology. 3(9)
Macrocyclization or stapling is one of the most well-known and generally applicable strategies for enhancing peptide/protein conformational stability and target binding affinity. However, there are limited structure- or sequence-based guidelines for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2546c92c7ea0d301d29ca70b62f06789
https://pubmed.ncbi.nlm.nih.gov/36128502
https://pubmed.ncbi.nlm.nih.gov/36128502