Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samantha A. Benjamin"'
Autor:
Courtney P. Jackson, Siteng Fang, Samantha R. Benjamin, Tchilabalo Alayi, Yetrib Hathout, Sarah M. Gillen, Jillian P. Handel, Brittany M. Brems, Justin M. Howe, L. Nathan Tumey
Publikováno v:
Bioorganicmedicinal chemistry letters. 75
In spite of their value in prodrug applications, the use of esters in antibody-drug-conjugate (ADC) payloads and linkers has generally been avoided due to the ubiquitous and promiscuous nature of human esterases. ADCs generally have a long circulatin
Autor:
William Darko, L. Nathan Tumey, Luke A. Probst, Christopher D. Miller, Robert W. Seabury, Samantha R. Benjamin, Risako Robinson, Pegah Shakeraneh, Wesley D Kufel
Publikováno v:
Hosp Pharm
Purpose: To evaluate the chemical and physical stability of an admixture containing cefepime and vancomycin in a single volume of lactated Ringer solution at refrigerated temperatures. Methods: Cefepime 2000 mg and vancomycin 1000 mg were, respective
Publikováno v:
Bioconjugate chemistry. 32(4)
Over the past two decades, antibody drug conjugates (ADCs) and small molecule drug conjugates (SMDCs) have widely employed valine-citruline and related cathepsin-cleavable linkers due to their stability in plasma and their rapid cleavage by lysosomal
Autor:
Zhongyuan Guo, L. Nathan Tumey, Siteng Fang, Courtney P. Jackson, Dane P. Carlson, Samantha R. Benjamin
Publikováno v:
Molecular pharmaceutics. 16(6)
Site-specific conjugation technology frequently relies on antibody engineering to incorporate rare or non-natural amino acids into the primary sequence of the protein. However, when the primary sequence is unknown or when antibody engineering is not
Autor:
Samantha A. Benjamin, Henry S. York
Publikováno v:
PMR : the journal of injury, function, and rehabilitation. 8(9S)
Autor:
Samantha A. Benjamin, Steven F. Harwin, Michael A. Mont, Paige E. Harrison, Anil Bhave, Jeffrey J. Cherian
Publikováno v:
The journal of knee surgery. 29(6)
Transcutaneous electrical nerve stimulation (TENS) has been shown to decrease pain associated with knee osteoarthritis, which potentially leads to better function, improved quality of life, and postpones the need for surgical intervention. The purpos