Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Samantha A Chow"'
Autor:
Zuleyha Ozen, M. Kyle Hadden, Samantha A Chow, Radha Charan Dash, Alessandro A. Rizzo, Kaitlyn R. McCarthy, Dmitry M. Korzhnev
Publikováno v:
Bioorganicmedicinal chemistry. 26(14)
Translesion synthesis (TLS) is a DNA damage tolerance mechanism that allows replicative bypass of DNA lesions, including DNA adducts formed by cancer chemotherapeutics. Previous studies demonstrated that suppression of TLS can increase sensitivity of