Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Samantha A Brugmann"'
Autor:
Kelsey H Elliott, Xiaoting Chen, Joseph Salomone, Praneet Chaturvedi, Preston A Schultz, Sai K Balchand, Jeffrey D Servetas, Aimée Zuniga, Rolf Zeller, Brian Gebelein, Matthew T Weirauch, Kevin A Peterson, Samantha A Brugmann
Publikováno v:
eLife, Vol 9 (2020)
Despite a common understanding that Gli TFs are utilized to convey a Hh morphogen gradient, genetic analyses suggest craniofacial development does not completely fit this paradigm. Using the mouse model (Mus musculus), we demonstrated that rather tha
Externí odkaz:
https://doaj.org/article/659f921a3e85487a949e94d7fb166cc9
Autor:
John Snedeker, Elizabeth N Schock, Jamie N Struve, Ching-Fang Chang, Megan Cionni, Pamela V Tran, Samantha A Brugmann, Rolf W Stottmann
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173258 (2017)
Primary cilia are organelles extended from virtually all cells and are required for the proper regulation of a number of canonical developmental pathways. The role in cortical development of proteins important for ciliary form and function is a relat
Externí odkaz:
https://doaj.org/article/2df64b1f400d41e59e1bebc42567e1fd
Autor:
Elizabeth N Schock, Jaime N Struve, Ching-Fang Chang, Trevor J Williams, John Snedeker, Aria C Attia, Rolf W Stottmann, Samantha A Brugmann
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174206 (2017)
Primary cilia are nearly ubiquitous, cellular projections that function to transduce molecular signals during development. Loss of functional primary cilia has a particularly profound effect on the developing craniofacial complex, causing several ano
Externí odkaz:
https://doaj.org/article/812c24cf00e7403e972be604bc294203
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006351 (2016)
Ciliopathies represent a broad class of disorders that affect multiple organ systems. The craniofacial complex is among those most severely affected when primary cilia are not functional. We previously reported that loss of primary cilia on cranial n
Externí odkaz:
https://doaj.org/article/7e81d240408e4dbbac9c1f8ff09f6620
Autor:
Andrea Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole Glidden, Ellen Roets, Jo Van Dorpe, Sandra Janssens, Danny E. Miller, Miranda Galey, Kari M. Brown, Rolf W. Stottmann, Sarah Vergult, K. Nicole Weaver, Samantha A. Brugmann, Timothy C. Cox, Justin Cotney
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Craniofacial abnormalities account for approximately one third of birth defects. The regulatory programs that build the face require precisely controlled spatiotemporal gene expression, achieved through tissue-specific enhancers. Clusters of
Externí odkaz:
https://doaj.org/article/d8bfbb8f7d514cd7a8d154657d67b4ca
Autor:
Kara E Powder, Yuan-Chieh Ku, Samantha A Brugmann, Rose A Veile, Nicole A Renaud, Jill A Helms, Michael Lovett
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35111 (2012)
Higher vertebrates use similar genetic tools to derive very different facial features. This diversity is believed to occur through temporal, spatial and species-specific changes in gene expression within cranial neural crest (NC) cells. These contrib
Externí odkaz:
https://doaj.org/article/cc928a63316f44f9a2d8c39886c3efda
Autor:
Aaron W James, Alexander A Theologis, Samantha A Brugmann, Yue Xu, Antoine L Carre, Philipp Leucht, Katherine Hamilton, Kenneth S Korach, Michael T Longaker
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7120 (2009)
While premature suture fusion, or craniosynostosis, is a relatively common condition, the cause is often unknown. Estrogens are associated with growth plate fusion of endochondral bones. In the following study, we explore the previously unknown signi
Externí odkaz:
https://doaj.org/article/ee7e9dd23dc649b0b24489e0e6042a0d
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
Ciliopathies represent a disease class characterized by a broad range of phenotypes including polycystic kidneys and skeletal anomalies. Ciliopathic skeletal phenotypes are among the most common and most difficult to treat due to a poor understanding
Externí odkaz:
https://doaj.org/article/abf3fe73d6d444b38e5f932bdb4f0016
Autor:
Kelsey H. Elliott, Sai K. Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M. Brown, Daniel T. Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A. Peterson, Samantha A. Brugmann
Publikováno v:
Development. 150
Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. Although the basic structure of the cilium and the cadre of genes that contribute to ciliary formation and function (the ciliome) are believed to be evolu
Autor:
Susanne I. Wells, Maura L. Gillison, Helmut Hanenberg, Elizabeth L. Virts, Randall J. Kimple, Paul F. Lambert, Samantha A. Brugmann, Kakajan Komurov, S. Steven Potter, Marion G. Brusadelli, Grant D. Foglesong, Lisa M. Privette Vinnedge, Elizabeth E. Hoskins, Lindsey E. Romick-Rosendale
Chick Chorioallantoic Membrane (CAM) assay for UM-SCC1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adad7588eafa1ddabcea4483398c56e9
https://doi.org/10.1158/1078-0432.22460474.v1
https://doi.org/10.1158/1078-0432.22460474.v1