Výsledky vyhledávání - "Samantha, Knodel"

Akademický článek

Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Publikováno v: Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)

Abstract Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome hav

Externí odkaz: https://doaj.org/article/1af3ea388c5e4f578c6b6afe6c865734

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Akademický článek

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

Publikováno v: Cell Reports, Vol 42, Iss 5, Pp 112474- (2023)

Summary: Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, t

Externí odkaz: https://doaj.org/article/7e7c96530b7143479c58b3f44a85ad62

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Akademický článek

Gut microbiome signatures linked to HIV-1 reservoir size and viremia control

Publikováno v: Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)

Abstract Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen with

Externí odkaz: https://doaj.org/article/f4eb4630f5eb4505a01baefcff14f0eb

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Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition

Autor: Yiran Wang, Laura Noël-Romas, Michelle Perner, Samantha Knodel, Refilwe Molatlhegi, Sarah Hoger, Kenzie Birse, Christina Farr Zuend, Lyle R McKinnon, Adam D Burgener

Publikováno v: Clinical Infectious Diseases. 76:1372-1381

Background Adolescent girls and young women aged 15‒24 years in sub-Saharan Africa are at disproportionate risk of human immunodeficiency virus (HIV) infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdee0657ddd93fc4da0949c022811c55
https://doi.org/10.1093/cid/ciac938

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Non-Lactobacillus dominant and polymicrobial vaginal microbiomes are more common in younger South African women and predictive of increased risk of HIV acquisition

Autor: Yiran, Wang, Laura, Noël-Romas, Michelle, Perner, Samantha, Knodel, Refilwe, Molatlhegi, Sarah, Hoger, Kenzie, Birse, Christina Farr, Zuend, Lyle R, McKinnon, Adam D, Burgener

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Adolescent girls and young women aged 15-24 in sub-Saharan Africa are at disproportionate risk of HIV infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility, we performed an age-stratified analysis of the va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eecdedb8d3c9a916ec2e9003b764558a
https://pubmed.ncbi.nlm.nih.gov/36504254

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Increased genital mucosal cytokines in Canadian women associates with increased antigen presenting cells, inflammatory metabolites, epithelial barrier disruption and the depletion of L. crispatus

Background: Cervicovaginal inflammation has been linked to negative reproductive health outcomes including acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e52252426642abe54cd934b54952cf18
https://doi.org/10.21203/rs.3.rs-1674482/v1

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