Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Samaneh Reiszadeh Jahromi"'
Publikováno v:
Parkinson's Disease, Vol 2021 (2021)
Parkinson’s disease (PD) is an age-associated neurodegenerative condition in which some genetic variants are known to increase disease susceptibility on interaction with environmental factors inducing oxidative stress. Different mutations in the SN
Externí odkaz:
https://doaj.org/article/76f979d1785c4f6dab139081a2d220af
Publikováno v:
Metabolic brain disease. 37(8)
Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. Although remarkable progress has been made in treating MS, current therapies are less effective in protecting against the progression of the disease. Since cucu
Autor:
Nima Sanadgol, Mohammad Reza Sepand, Samaneh Ramezani-sefidar, Meysam Yazdankhah, Mohsen Shahlaei, Sajad Moradi, Samaneh Reiszadeh-Jahromi
Publikováno v:
Neurochemical Research. 44:2482-2498
Cuprizone (cup) model targets oligodendrocytes (OLGs) degeneration and is frequently used for the mechanistic understanding of de- and remyelination. Improperly, this classic model is time-consuming and the extent of brain lesions and behavioral defi
Publikováno v:
Parkinson's Disease
Parkinson's Disease, Vol 2021 (2021)
Parkinson's Disease, Vol 2021 (2021)
Parkinson’s disease (PD) is an age-associated neurodegenerative condition in which some genetic variants are known to increase disease susceptibility on interaction with environmental factors inducing oxidative stress. Different mutations in the SN
Parkinson’s disease (PD) is a class of neurodegenerative disorders in which, complex interactions of genetic and environmental agents are involved in the etiology of both sporadic and familial PD cases. α-synuclein-encodingSNCAgene is known as one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb85392e30597fb984f9d0e042c7f279
Publikováno v:
Neurochemistry International. 80:1-6
Overexpression of human α-synuclein gene in Drosophila can reduce lifespan, and we have performed lifespan assay for A30P and A53Tα-synuclein transgenic and control (elav-GAL4, UAS-A30P, UAS-A53T) flies. Our results showed reduced lifespan of trans
Autor:
Mohammad Haddadi, Samaneh Reiszadeh Jahromi, Saraf R. Ramesh, Upendra Nongthomba, Thimmappa Shivanandappa
Publikováno v:
Neurochemistry international. 100
Oxidative stress is one of the major etiological factors implicated in pathogenesis of neurodegenerative diseases. Since neurons are more sensitive to oxidative damage there is an increasing interest in developing novel antioxidant therapies, especia
Publikováno v:
Behavioural brain research. 301
The e4 isoform of apolipoprotein E (ApoE4) that is involved in neuron-glial lipid metabolism has been demonstrated as the main genetic risk factor in late-onset of Alzheimer's disease. However, the mechanism underlying ApoE4-mediated neurodegeneratio
Publikováno v:
Neuroscience. 293
Oxidative stress is believed to be a major factor for the onset of Parkinson’s disease (PD). In this study, we have investigated oxidative status in transgenic Drosophila model of PD. Our results revealed elevated levels of reactive oxygen species
Autor:
Thimmappa Shivanandappa, Saraf R. Ramesh, B K Chandrasekhar Sagar, Samaneh Reiszadeh Jahromi, Mohammad Haddadi, Rajashekhar K. Patil
Publikováno v:
Behavioural brain research. 259
Memory impairment during aging is believed to be a consequence of decline in neuronal function and increase in neurodegeneration. Accumulation of oxidative damage and reduction of antioxidant defense system play a key role in organismal aging and fun