Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Saman M. Najmi"'
Autor:
Jasmine M. Miller-Kleinhenz, Alexandra B. Kuzmishin Nagy, Ania A. Majewska, Adeola O. Adebayo Michael, Saman M. Najmi, Karena H. Nguyen, Robert E. Van Sciver, Ida T. Fonkoue
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Jasmine Miller-Kleinhenz et al. highlight the risk of science and academia’s general neutrality to discussions around race and social justice. Their collectively-developed course represents a framework to begin these important discussions and impro
Externí odkaz:
https://doaj.org/article/9c7999ce438d4474bb1293370bd022af
Autor:
Ting Wei, Saman M. Najmi, Hester Liu, Karita Peltonen, Alena Kucerova, David A. Schneider, Marikki Laiho
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 404-414 (2018)
Summary: Inhibition of RNA polymerase I (Pol I) is a promising strategy for modern cancer therapy. BMH-21 is a first-in-class small molecule that inhibits Pol I transcription and induces degradation of the enzyme, but how this exceptional response is
Externí odkaz:
https://doaj.org/article/b248a058d79f4f92b95067000835da03
Autor:
Brittany L Ford, Ting Wei, Hester Liu, Catherine E Scull, Saman M Najmi, Stephanie Pitts, Wenjun Fan, David A Schneider, Marikki Laiho
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285660 (2023)
RNA Polymerase I (Pol I) has recently been recognized as a cancer therapeutic target. The activity of this enzyme is essential for ribosome biogenesis and is universally activated in cancers. The enzymatic activity of this multi-subunit complex resid
Externí odkaz:
https://doaj.org/article/deb9e959af1549c0995c621a11a4bf5f
Autor:
Ania A. Majewska, Jasmine Miller-Kleinhenz, Ida T. Fonkoue, Adeola O. Adebayo Michael, Karena H. Nguyen, Saman M. Najmi, Alexandra B. Kuzmishin Nagy, Robert E. Van Sciver
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Jasmine Miller-Kleinhenz et al. highlight the risk of science and academia’s general neutrality to discussions around race and social justice. Their collectively-developed course represents a framework to begin these important discussions and impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc36064f0203a90a6f49a189894ceda
http://europepmc.org/articles/PMC8342502
http://europepmc.org/articles/PMC8342502
Autor:
Saman M. Najmi, David A. Schneider
Publikováno v:
Gene
Ribosome biogenesis requires the concerted activities of three nuclear RNA polymerases, (Pols) I, II, and III, to produce 25S, 18S and 5.8S ribosomal RNA (rRNA), messenger RNA (mRNA) encoding ribosomal proteins, and the 5S rRNA, respectively. The rRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1258331178365486803efe825b7bf3
https://pubmed.ncbi.nlm.nih.gov/33482283
https://pubmed.ncbi.nlm.nih.gov/33482283
In eukaryotic cells, nuclear RNA synthesis is accomplished by at least three unique, multisubunit RNA polymerases. The roles of these enzymes are generally partitioned into the synthesis of the three major classes of RNA: rRNA, mRNA, and tRNA for RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069d4fd231ef43a1661bfd78e1a73ebc
https://europepmc.org/articles/PMC5280279/
https://europepmc.org/articles/PMC5280279/
