Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Saman Hosseinkhani"'
Autor:
Mohammad Hashemabadi, Hossein Ali Sasan, Saman Hosseinkhani, Mojdeh Amandadi, Azadeh Samareh Gholami, Majid Sadeghizadeh
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The CRISPR system finds extensive application in molecular biology, but its continuous activity can yield adverse effects. Leveraging programmable CRISPR/Cas9 function via nano-device mediation effectively mitigates these drawbacks. The inte
Externí odkaz:
https://doaj.org/article/7ce87d3c6e5b4865b7a1cc9a7448369c
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-22 (2024)
Abstract Despite the many mechanisms it has created to prevent unfolding and aggregation of proteins, many diseases are caused by abnormal folding of proteins, which are called misfolding diseases. During this process, proteins undergo structural cha
Externí odkaz:
https://doaj.org/article/f25a93632b3e4ae48072f1cf803ed9ba
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101121- (2024)
Chimeric antigen receptor T (CAR-T) cell therapy represents a breakthrough in personalized cancer treatments. In this regard, synthetic receptors comprised of antigen recognition domains, signaling, and stimulatory domains are used to reprogram T-cel
Externí odkaz:
https://doaj.org/article/e71397b3681e4c3083e7c4de8dde7583
Autor:
Mohadeseh Khoshandam, Hossein Soltaninejad, Marziyeh Mousazadeh, Amir Ali Hamidieh, Saman Hosseinkhani
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 268-282 (2024)
CRISPR/Cas9 is an effective gene editing tool with broad applications for the prevention or treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced short palindromic repeats) as a bacterial immune system and plays as a g
Externí odkaz:
https://doaj.org/article/a480fc411a3e49abb2d077a999880501
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In the study, a biomimetic platform for anti-inflammatory-based treatment of atherosclerotic plaque was developed. Gliclazide (GL) as an anti-inflammasome agent was encapsulated in PLGA nanoparticles (NP), which were coated by monocyte membr
Externí odkaz:
https://doaj.org/article/5d3102d05a9d45d283acc70193277714
Autor:
Ying Sun, Wenchao Hu, Song Zhang, Yanjin Lu, Jie Wang, Guangcai Ma, Jinxin Lin, Saman Hosseinkhani, Jia Ma, Qiang Wang
Publikováno v:
Journal of Materials Research and Technology, Vol 23, Iss , Pp 1630-1643 (2023)
Implants are commonly used to replace damaged bones in the human body. Fatigue failure is one of the most serious issues with implants. Understanding the underlying mechanisms that lead to fatigue failure is crucial in ensuring the longevity of bioma
Externí odkaz:
https://doaj.org/article/181e0b2e3f114a268bb6295ac3c27894
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115299- (2023)
Genomic DNA sequences provide unique target sites, with high druggability value, for treatment of genetically-linked diseases like cancer. B-cell lymphoma protein-2 (BCL-2) prevents Bcl-2-associated X protein (BAX) and Bcl-2 antagonist killer 1 (BAK)
Externí odkaz:
https://doaj.org/article/cfd217949a554599a840e61aa07fc0d7
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19429- (2023)
Fe3O4@SiO2@NiAl-LDH three-components microsphere contains a Fe3O4@SiO2 magnetic core and a layered double hydroxide with nickel cation provide the binding ability to (His)-tagged-protein and exhibits high performance in protein separation and purific
Externí odkaz:
https://doaj.org/article/c06ad1ef4b5d454fb385161f95cb2cf2
'Plasmonic Nanomaterials': An emerging avenue in biomedical and biomedical engineering opportunities
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 61-71 (2022)
Background: Plasmonic nanomaterials as noble metal-based materials have unique optical characteristic upon exposure to incident light with an appropriate wavelength. Today, generated plasmon by nanoparticles has received increasing attention in nanom
Externí odkaz:
https://doaj.org/article/0a35704528f74970866f5a4776603a38
Autor:
Shima Lotfollahzadeh, Elaheh Sadat Hosseini, Hooman Mahmoudi Aznaveh, Maryam Nikkhah, Saman Hosseinkhani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL), known as a cytokine of the TNF superfamily, is considered a promising antitumor agent due to its ability to selectively induce apoptosis in a wide variety of cancer cells
Externí odkaz:
https://doaj.org/article/f71aaeb74a0c489bb190afc09530c72c