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pro vyhledávání: '"Saman Bazmi"'
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Macromolecular crowding effects on globular proteins, which usually adopt a single stable fold, have been widely studied. However, little is known about crowding effects on fold-switching proteins, which reversibly switch between distinct fo
Externí odkaz:
https://doaj.org/article/8d7297f8c60746fb9e39f4578e866060
Autor:
Saman Bazmi, Stefan Wallin
Publikováno v:
PeerJ Physical Chemistry, Vol 6, p e31 (2024)
The equilibrium stability of a protein is determined by its amino acid sequence and the solution conditions, such as temperature, pH and presence of chemical denaturant. The stability of a single protein in two identical solutions can nonetheless dif
Externí odkaz:
https://doaj.org/article/95903942e59c4414841dd5fe7579542b
Publikováno v:
Macromolecules. 55:9103-9112
Autor:
Saman Bazmi, Stefan Wallin
Publikováno v:
Biophys J
It is generally assumed that volume exclusion by macromolecular crowders universally stabilizes the native states of proteins and destabilization suggests soft attractions between crowders and protein. Here we show that proteins can be destabilized e