AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.

Autor: Crosas-Molist E; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Graziani V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Maiques O; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Pandya P; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Monger J; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Samain R; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., George SL; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Malik S; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Salise J; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Morales V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Le Guennec A; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Atkinson RA; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK.; Institut de Pharmacologie et de Biologie Structurale (IPBS), UMR5089, CNRS-Université de Toulouse III-Paul Sabatier, BP 64182, 31077, Toulouse, Cedex 4, France., Marti RM; Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, CIBERONC, IRB Lleida, Lleida, 25198, Spain., Matias-Guiu X; Department of Pathology and Molecular Genetics, Hospital Universitari Arnau de Vilanova, University of Lleida, IRB Lleida, CIBERONC, Lleida, 25198, Spain.; Department of Pathology, Hospital Universitari de Bellvitge, University of Barcelona, IDIBELL, CIBERONC, L'Hospitalet de Llobregat, Barcelona, 08907, Spain., Charras G; London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK.; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK., Conte MR; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Elosegui-Artola A; Cell and Tissue Mechanobiology Lab, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Department of Physics, King's College London, London, WC2R 2LS, UK., Holt M; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; School of Cardiovascular and Metabolic Medicine & Sciences, King's College London BHF Centre of Research Excellence, London, SE1 1UL, UK., Sanz-Moreno V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK. v.sanz-moreno@qmul.ac.uk.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK. v.sanz-moreno@qmul.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2023 May 22; Vol. 14 (1), pp. 2740. Date of Electronic Publication: 2023 May 22.

Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma.

Autor: Neuzillet C; Department of Medical Oncology, Institut Curie, Université Versailles Saint-Quentin, Paris Saclay, Saint-Cloud, France.; UMR144, Institut Curie, Paris, France., Nicolle R; INSERM U1149, Centre de Recherche sur l'Inflammation, Paris, France., Raffenne J; INSERM UMR-1037, Cancer Research Center of Toulouse (CRCT), Team 'labellisée Ligue Contre le Cancer', University of Toulouse, Toulouse, France., Tijeras-Raballand A; OncoMEGA, Lamorlaye, France., Brunel A; INSERM UMR-1037, Cancer Research Center of Toulouse (CRCT), Team 'labellisée Ligue Contre le Cancer', University of Toulouse, Toulouse, France., Astorgues-Xerri L; OncoMEGA, Lamorlaye, France., Vacher S; Department of Genetics, Institut Curie, PSL Research University, Paris, France., Arbateraz F; Centre d'Histologie Imagerie et Cytométrie (CHIC), U1138 Centre de Recherche des Cordeliers (CRC), Paris, France., Fanjul M; INSERM UMR-1037, Cancer Research Center of Toulouse (CRCT), Team 'labellisée Ligue Contre le Cancer', University of Toulouse, Toulouse, France., Hilmi M; Department of Medical Oncology, Institut Curie, Université Versailles Saint-Quentin, Paris Saclay, Saint-Cloud, France., Samain R; INSERM UMR-1037, Cancer Research Center of Toulouse (CRCT), Team 'labellisée Ligue Contre le Cancer', University of Toulouse, Toulouse, France., Klein C; Centre d'Histologie Imagerie et Cytométrie (CHIC), U1138 Centre de Recherche des Cordeliers (CRC), Paris, France., Perraud A; Department of Digestive Surgery, University Hospital of Limoges, Limoges, France.; INSERM UMLR-1308, University of Limoges, Limoges, France., Rebours V; INSERM U1149, Centre de Recherche sur l'Inflammation, Paris, France.; Department of Pancreatology, Beaujon Hospital (APHP), Clichy-La-Garenne, France., Mathonnet M; Department of Digestive Surgery, University Hospital of Limoges, Limoges, France.; INSERM UMLR-1308, University of Limoges, Limoges, France., Bièche I; Department of Genetics, Institut Curie, PSL Research University, Paris, France., Kocher H; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, London, UK., Cros J; INSERM U1149, Centre de Recherche sur l'Inflammation, Paris, France.; Department of Pathology, Beaujon Hospital (APHP), Université de Paris, Paris, France., Bousquet C; INSERM UMR-1037, Cancer Research Center of Toulouse (CRCT), Team 'labellisée Ligue Contre le Cancer', University of Toulouse, Toulouse, France.

Publikováno v: The Journal of pathology [J Pathol] 2022 Dec; Vol. 258 (4), pp. 408-425. Date of Electronic Publication: 2022 Oct 21.

Pancreatic cancer patient-derived xenograft (PDX) RNAseq analyses to unravel the stromal impact on gemcitabin resistance acquisition

Autor: Raffenne, J., Samain, R., Alard, A., Brunel, A., Belhabib, I., Theillet, C., Martineau, Y., Pyronnet, S., Jean, C., Nicolle, R., Bousquet, C.

Publikováno v: In Pancreatology July 2021 21 Supplement 1:S69-S69

Deciphering pancreatic Cancer-Associated Fibroblasts biology for therapeutic targeting of pancreatic adenocarcinoma

Autor: Samain, R., Decaup, E., Zaghoudi, S., Rochotte, J., Cassant-Sourdy, S., Perraud, A.P., Mathonnet, M., Schmid, H., Martineau, Y., Pyronnet, S., Jean, C., Bousquet, C.

Publikováno v: In Pancreatology December 2020 20(8):e5-e6

The axis of tumor-associated macrophages, extracellular matrix proteins, and cancer-associated fibroblasts in oncogenesis.

Autor: Yu, Shuhong¹ (AUTHOR), Wang, Siyu¹ (AUTHOR), Wang, Xuanyu² (AUTHOR), Xu, Ximing¹ (AUTHOR) doctorxu120@aliyun.com

Publikováno v: Cancer Cell International. 10/7/2024, Vol. 24 Issue 1, p1-30. 30p.