Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samah Neame"'
Autor:
Marialaura Marchetti, Hazem Safory, Shai Kellner, Simone Engelender, Shai Berlin, Inna Radzishevsky, Veronika N. Foltyn, Samah Neame, Francesco Marchesani, Ayelet Touitou, Jean-Marie Billard, Herman Wolosker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (41), pp.20736-20742. ⟨10.1073/pnas.1909458116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (41), pp.20736-20742. ⟨10.1073/pnas.1909458116⟩
Astrocytes express the 3-phosphoglycerate dehydrogenase (Phgdh) enzyme required for the synthesis of l-serine from glucose. Astrocytic l-serine was proposed to regulate NMDAR activity by shuttling to neurons to sustain d-serine production, but this h
Asc-1 transporter regulation of synaptic activity via the tonic release of D-serine in the forebrain
Autor:
Hazem Safory, Eitan Kaplan, Jean-Marie Billard, Christoffer Bundgaard, Christian Thomsen, Avi Avital, Hagit Sason, Salman Zubedat, Samah Neame, Kenneth Vielsted Christensen, Dina Rosenberg, Claus Tornby Christoffersen, Garrick Paul Smith, Herman Wolosker, Veronika N. Foltyn
Publikováno v:
Cerebral Cortex
Cerebral Cortex, Oxford University Press (OUP), 2017, 27 (2), pp.1573-1587. ⟨10.1093/cercor/bhv350⟩
Cerebral Cortex, Oxford University Press (OUP), 2017, 27, pp.1573-1587. ⟨10.1177/0271678X15626718⟩
Cerebral Cortex, Oxford University Press (OUP), 2017, 27 (2), pp.1573-1587. ⟨10.1093/cercor/bhv350⟩
Cerebral Cortex, Oxford University Press (OUP), 2017, 27, pp.1573-1587. ⟨10.1177/0271678X15626718⟩
d-Serine is a co-agonist of NMDA receptors (NMDARs) whose activity is potentially regulated by Asc-1 (SLC7A10), a transporter that displays high affinity for d-serine and glycine. Asc-1 operates as a facilitative transporter and as an antiporter, tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e811a43353d2e0dd0cbd67c9faf985c
https://hal-normandie-univ.archives-ouvertes.fr/hal-02325027
https://hal-normandie-univ.archives-ouvertes.fr/hal-02325027
Autor:
Yoav Shulman, Herman Wolosker, Dina Rosenberg, Samah Neame, Salman Zubedat, Simone Engelender, Hazem Safory, Jackie Schiller, Avi Avital, Swen Hülsmann, Inna Radzishevsky, Hagit Sason
Publikováno v:
EMBO reports. 16(5)
Asc-1 (SLC7A10) is an amino acid transporter whose deletion causes neurological abnormalities and early postnatal death in mice. Using metabolomics and behavioral and electrophysiological methods, we demonstrate that Asc-1 knockout mice display a mar