SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress

Autor: Abdallah Zayed, Camille Baranowski, Anne-Claire Compagnion, Cécile Vernochet, Samah Karaki, Romain Durand-de Cuttoli, Estefani Saint-Jour, Soumee Bhattacharya, Fabio Marti, Peter Vanhoutte, Moshe Yaniv, Philippe Faure, Jacques Barik, Laurence Amar, François Tronche, Sébastien Parnaudeau

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Repeated exposure to social stressors in rodents results in behavioural changes. Here the authors show that behavioural adaptations to stress are associated with nuclear organization changes through SWI/SNF chromatin remodeler in specific neuronal po

Externí odkaz: https://doaj.org/article/f7c1519f7db7481caf0f4a105de4bb4d

Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser 280 by Hallucinogenic versus Nonhallucinogenic Agonists

Autor: Carine Bécamel, Samy Murat, Philippe Marin, Clotilde Mannoury la Cour, Samah Karaki, Franck Vandermoere, Laurent Prézeau, Millan Mark, Joël Bockaert

Publikováno v: Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2014, 13 (5), pp.1273-1285. ⟨10.1074/mcp.M113.036558⟩
Molecular & Cellular Proteomics : MCP

International audience; The serotonin 5-HT 2A receptor is a primary target of psy-chedelic hallucinogens such as lysergic acid diethyl-amine, mescaline, and psilocybin, which reproduce some of the core symptoms of schizophrenia. An incompletely resol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76404e2eb1fcbde4a8814d7230dd74e8
https://hal.archives-ouvertes.fr/hal-02366017