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Autor:
Krzysztof Palczewski, Alyaa Shmara, Timothy Ton, Cheng Cheng, Jesse D. Vargas, Marja Pitkänen, Virginia Kimonis, Lan Weiss, Teemu Turunen, Sama Saeid, Christopher L. Sander, Henri Leinonen, Lac Ta, Jianye Zhang, Ari Koskelainen
Publikováno v:
J Pharmacol Exp Ther
CB-5083 is an inhibitor of p97/valosin-containing protein (VCP), for which phase I trials for cancer were terminated because of adverse effects on vision, such as photophobia and dyschromatopsia. Lower dose CB-5083 could combat inclusion body myopath