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Membrane-bound HSP70-engineered myeloma cell-derived exosomes stimulate more efficient CD8+ CTL- and NK-mediated antitumour immunity than exosomes released from heat-shocked tumour cells expressing cytoplasmic HSP70

Autor: Karen Slattery, Ou Bai, Rajni Chibbar, Yulin Deng, Jinying Yuan, Yufeng Xie, Mabood Qureshi, Jim Xiang, Sam Zong, Yangdou Wei, Haifeng Zhang

Publikováno v: Journal of Cellular and Molecular Medicine

Exosomes (EXO) derived from tumour cells have been used to stimulate antitumour immune responses, but only resulting in prophylatic immunity. Tumour-derived heat shock protein 70 (HSP70) molecules are molecular chaperones with a broad repertoire of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44549fc41d442c79f5a246e2d201f47a
http://europepmc.org/articles/PMC4373481

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CD4+ T cell acquisition of the bystander pMHC I colocalizing in the same immunological synapse comprising pMHC II and costimulatory CD40, CD54, CD80, OX40L, and 41BBL

Autor: Tianpei He, Jim Xiang, Xiaochu Wu, Yangdou Wei, Sam Zong

Publikováno v: Biochemical and biophysical research communications. 362(4)

We previously showed that CD4+ T cells acquired peptide/major histocompatibility complex (pMHC) I and costimulatory molecules by dendritic cell (DC) activation. However, the molecular mechanism for pMHC I acquisition is unclear. In this study, by usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4f43454aff1d18a4d5f42925c8f0c5
https://pubmed.ncbi.nlm.nih.gov/17803957

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Developing a computerized data collection and decision support system for cancer pain management

Autor: Stuart Farber, Daniela Hairabedian, M. Kay M. Judge, Donna L. Berry, Shi Ping Sam Zong, Diana J. Wilkie, Charles Chabal, Hsiu Ying Huang

Publikováno v: Computers, informatics, nursing : CIN. 21(4)

Contemporary nursing practice needs reengineering to deliver its service effectively and efficiently. Using computer technology to support clinicians' decision making may be a parsimonious way to provide high-quality, patient-centered, efficient care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f4937935bdc9df5afcbede1db839d3
https://pubmed.ncbi.nlm.nih.gov/12869874

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Akademický článek

Developing a Computerized Data Collection and Decision Support System for Cancer Pain Management.

Autor: HSIU-YING HUANG, DIANA J. WILKIE, SHI-PING (SAM) ZONG, DONNA BERRY, DANIELA HAIRABEDIAN, M. KAY JUDGE, STUART FARBER, CHARLES CHABAL

Publikováno v: CIN: Computers, Informatics, Nursing; Jul/Aug2003, Vol. 21 Issue 4, p206-217, 12p

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