A multicentre randomised controlled trial of a guided self-help cognitive behavioural therapy to MANage the impact of hot flushes and night sweats in patients with prostate CANcer undergoing androgen deprivation therapy (MANCAN2)

Autor: Simon Crabb, Alannah Morgan, Myra S. Hunter, Evgenia Stefanopoulou, Gareth Griffiths, Alison Richardson, Deborah Fenlon, Louisa Fleure, James Raftery, Cherish Boxall, Sam Wilding, Jacqueline Nuttall, Zina Eminton, Emma Tilt, Alice O’Neill, Roger Bacon, Jonathan Martin

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-12 (2023)

Abstract Background Androgen deprivation therapy (ADT) is prescribed to almost half of all men diagnosed with prostate cancer. Although ADT is effective treatment, with virtually all men with advanced disease showing initial clinical response, it is

Externí odkaz: https://doaj.org/article/2787de21ffe84cb78c69feb030d9a3cb

Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial

Autor: Merlin Willcox, Catherine Simpson, Sam Wilding, Beth Stuart, Dia Soilemezi, Amy Whitehead, Alannah Morgan, Emma Wrixon, Shihua Zhu, Guiqing Yao, Fran Webley, Ruiyang Yan, Jennifer Bostock, Margaret Bell, Gareth Griffiths, Geraldine Leydon, Paul Little, Christopher Butler, Alastair D. Hay, Michael Moore

Publikováno v: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-16 (2021)

Abstract Background Pelargonium sidoides DC (Geraniaceae) root extract, EPs®7630 or “Kaloba®”, is a widely used herbal remedy for respiratory infections, with some evidence of effectiveness for acute bronchitis. However, it is not yet widely re

Externí odkaz: https://doaj.org/article/ac120b8311764d5ca70b7034e3694d87

Are environmental area characteristics at birth associated with overweight and obesity in school-aged children? Findings from the SLOPE (Studying Lifecourse Obesity PrEdictors) population-based cohort in the south of England

Autor: Sam Wilding, Nida Ziauddeen, Dianna Smith, Paul Roderick, Debbie Chase, Nisreen A. Alwan

Publikováno v: BMC Medicine, Vol 18, Iss 1, Pp 1-13 (2020)

Abstract Background Geographical inequalities in overweight and obesity prevalence among children are well established in cross-sectional research. We aimed to examine how environmental area characteristics at birth are related to these outcomes in c

Externí odkaz: https://doaj.org/article/479d26a7819a46b7973f06879709f5de

Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs

Autor: Mark A. Hlatky, Sam Wilding, Beth Stuart, Zoe Nicholas, James Shambrook, Zina Eminton, Kim Fox, Derek Connolly, Peter O'Kane, Alex Hobson, Anoop Chauhan, Neal Uren, Gerry P. Mccann, Colin Berry, Justin Carter, Carl Roobottom, Mamas Mamas, Ronak Rajani, Ian Ford, Pamela S. Douglas, Nick Curzen

Publikováno v: Journal of Cardiovascular Computed Tomography. 17:52-59

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc65d3662160ef56549dcc32edae27a1
https://doi.org/10.1016/j.jcct.2022.09.005

Differential Efficacy From the Addition of Bortezomib to R-CHOP in Diffuse Large B-Cell Lymphoma According to the Molecular Subgroup in the REMoDL-B Study With a 5-Year Follow-Up

Autor: Andrew J. Davies, Sharon Barrans, Louise Stanton, Josh Caddy, Sam Wilding, Geoff Saunders, Christoph Mamot, Urban Novak, Andrew McMillan, Paul Fields, Graham P. Collins, Richard Stephens, Francesco Cucco, Chulin Sha, Moniek van Hoppe, Reuben Tooze, John R. Davies, Gareth Griffiths, Anna Schuh, Catherine Burton, David R. Westhead, Ming-Qing Du, Peter W.M. Johnson

Publikováno v: Davies, Andrew J; Barrans, Sharon; Stanton, Louise; Caddy, Josh; Wilding, Sam; Saunders, Geoff; Mamot, Christoph; Novak, Urban; McMillan, Andrew; Fields, Paul; Collins, Graham P; Stephens, Richard; Cucco, Francesco; Sha, Chulin; van Hoppe, Moniek; Tooze, Reuben; Davies, John R; Griffiths, Gareth; Schuh, Anna; Burton, Catherine; ... (2023). Differential Efficacy From the Addition of Bortezomib to R-CHOP in Diffuse Large B-Cell Lymphoma According to the Molecular Subgroup in the REMoDL-B Study With a 5-Year Follow-Up. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 41(15), pp. 2718-2723. American Society of Clinical Oncology 10.1200/JCO.23.00033

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6393d74e85b1c2b6a31b21155d2ee789