Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sam Weissman"'
Publikováno v:
Pathogens and Immunity, Vol 8, Iss 2 (2024)
Background: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strategies, we and others have focused on understanding the selection pressures exerted on the reservoir by
Externí odkaz:
https://doaj.org/article/1daacb0028114ff39505fc2386e9139f
Autor:
Marilia R. Pinzone, Sam Weissman, Alexander O. Pasternak, Ryan Zurakowski, Stephen Migueles, Una O’Doherty
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
Historically, naive cells have been considered inconsequential to HIV persistence. Here, we compared the contributions of naive and memory cells to the reservoirs of individuals with a spectrum of reservoir sizes and variable immunological control. W
Externí odkaz:
https://doaj.org/article/07e18e798f2e4473be66cf7c80da6216
Autor:
Marilia Rita Pinzone, D. Jake VanBelzen, Sam Weissman, Maria Paola Bertuccio, LaMont Cannon, Emmanuele Venanzi-Rullo, Stephen Migueles, R. Brad Jones, Talia Mota, Sarah B. Joseph, Kevin Groen, Alexander O. Pasternak, Wei-Ting Hwang, Brad Sherman, Anastasios Vourekas, Giuseppe Nunnari, Una O’Doherty
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
How HIV reservoirs are shaped over time on antiviral therapy is poorly understood. Here, the authors analyze the dynamics of the HIV reservoir by longitudinal proviral sequencing revealing that HIV reservoir expression can contribute to its clearance
Externí odkaz:
https://doaj.org/article/bcf0eb263eba47799a2cae2421234886
Autor:
Emmanuele Venanzi Rullo, Marilia Rita Pinzone, LaMont Cannon, Sam Weissman, Manuela Ceccarelli, Ryan Zurakowski, Giuseppe Nunnari, Una O’Doherty
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Despite the efficacy of antiretroviral therapy (ART), HIV persists in a latent form and remains a hurdle to eradication. CD4+ T lymphocytes harbor the majority of the HIV reservoir, but the role of individual subsets remains unclear. CD4+ T cells wer
Externí odkaz:
https://doaj.org/article/3420deeaca514f978eefbad384131d6d
Autor:
Una O'Doherty, Stephen A. Migueles, Alexander O. Pasternak, Marilia Rita Pinzone, Sam Weissman, Ryan Zurakowski
Publikováno v:
JCI insight, 6(16):e150794. The American Society for Clinical Investigation
JCI Insight
JCI Insight
Historically, naive cells have been considered inconsequential to HIV persistence. Here, we compared the contributions of naive and memory cells to the reservoirs of individuals with a spectrum of reservoir sizes and variable immunological control. W
Autor:
Alexander O. Pasternak, Giuseppe Nunnari, Una O'Doherty, Brad T. Sherman, Marilia Rita Pinzone, LaMont Cannon, D. Jake VanBelzen, R. Brad Jones, Talia M. Mota, Stephen A. Migueles, Sam Weissman, Kevin Groen, Emmanuele Venanzi-Rullo, Anastasios Vourekas, Sarah B. Joseph, Wei-Ting Hwang, Maria Paola Bertuccio
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature communications, 10(1):728. Nature Publishing Group
Nature Communications
Nature communications, 10(1):728. Nature Publishing Group
After initiating antiretroviral therapy (ART), a rapid decline in HIV viral load is followed by a long period of undetectable viremia. Viral outgrowth assay suggests the reservoir continues to decline slowly. Here, we use full-length sequencing to lo
Autor:
Manuela Ceccarelli, Emmanuele Venanzi Rullo, Sam Weissman, Ryan Zurakowski, Marilia Rita Pinzone, LaMont Cannon, Giuseppe Nunnari, Una O'Doherty
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
JCI Insight
Despite the efficacy of antiretroviral therapy (ART), HIV persists in a latent form and remains a hurdle to eradication. CD4+ T lymphocytes harbor the majority of the HIV reservoir, but the role of individual subsets remains unclear. CD4+ T cells wer
Autor:
LaMont Cannon, Sam Weissman, D. Jake VanBelzen, Maria Paola Bertuccio, Una O'Doherty, Wei-Ting Hwang, Marilia Rita Pinzone, Brad T. Sherman
After initiating antiretroviral therapy (ART), a rapid decline in plasma viremia is followed by reservoir stabilization. Viral outgrowth assay suggests the reservoir continues to decline slowly, but variation over time and among individuals complicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36478b57ba0bb88c05661be013c3088f
Autor:
Simmy Bank, Anant Vk Indaram, Santa Nandi, Ronald Greenberg, Meyer Blumstein, Sing Lam, Sam Weissman, Beverly Bailey
Publikováno v:
World Journal of Gastroenterology. 6:49
AIM:To determine levels of cytokines in colonic mucosa of asymptomatic first degree relatives of Crohn's disease patients.METHODS:Cytokines (Interleukin (IL) 1-Beta, IL-2, IL-6 and IL-8) were measured using ELISA in biopsy samples of normal looking c