Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes.

Autor: Dostalek M, Sam WJ, Paryani KR, Macwan JS, Gohh RY, Akhlaghi F, Dostalek, Miroslav, Sam, Wai-Johnn, Paryani, Komal R, Macwan, Joyce S, Gohh, Reginald Y, Akhlaghi, Fatemeh

Publikováno v: Clinical Pharmacokinetics; 2012, Vol. 51 Issue 9, p591-606, 16p

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Effects of SLC22A1 Polymorphisms on Metformin-Induced Reductions in Adiposity and Metformin Pharmacokinetics in Obese Children With Insulin Resistance.

Autor: Sam WJ; Clinical Pharmacokinetics Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD, USA., Roza O; Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.; Institute of Pharmacognosy, University of Szeged, Szeged, Hungary., Hon YY; Clinical Pharmacokinetics Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD, USA.; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Alfaro RM; Clinical Pharmacokinetics Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD, USA., Calis KA; Clinical Pharmacokinetics Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD, USA.; Office of the Clinical Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Reynolds JC; Nuclear Medicine Division, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA., Yanovski JA; Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 2017 Feb; Vol. 57 (2), pp. 219-229. Date of Electronic Publication: 2016 Aug 23.

The role of mitochondrial bioenergetics and reactive oxygen species in coronary collateral growth.

Autor: Pung YF; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, Ohio., Sam WJ, Hardwick JP, Yin L, Ohanyan V, Logan S, Di Vincenzo L, Chilian WM

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2013 Nov 01; Vol. 305 (9), pp. H1275-80. Date of Electronic Publication: 2013 Aug 30.

Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients.

Autor: Sam WJ; Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD 20892, USA., Chamberlain CE, Lee SJ, Goldstein JA, Hale DA, Mannon RB, Kirk AD, Hon YY

Publikováno v: Transplantation [Transplantation] 2012 Nov 15; Vol. 94 (9), pp. 971-7.