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pro vyhledávání: '"Sam Sorof"'
Autor:
Sam Sorof
Publikováno v:
Cancer and Metastasis Reviews. 13:317-336
Liver fatty acid binding protein (L-FABP), a cytoplasmic 14 kDa protein previously termed Z protein, is conventionally considered to be an intracellular carrier of fatty acids in rat hepatocytes. The following evidence now indicates that L-FABP is al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6902661ffef3946fc6364263991e1be8
https://doi.org/10.1007/bf00666102
https://doi.org/10.1007/bf00666102
Autor:
Shahid H. Khan, Sam Sorof
Publikováno v:
Proceedings of the National Academy of Sciences. 91:848-852
Peroxisome proliferators (PP) are a diverse group of chemicals that induce dramatic increases in peroxisomes in rodent hepatocytes, followed by hypertrophy, hepatomegaly, alterations in lipid metabolism, mitogenesis, and finally hepatocarcinomas. Ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dde6d5f9da6ae0b5f28b5bb2b0817b
https://doi.org/10.1073/pnas.91.3.848
https://doi.org/10.1073/pnas.91.3.848
Autor:
Tibor Keler, Sam Sorof
Publikováno v:
Journal of Cellular Physiology. 157:33-40
Former studies have linked hepatocyte growth with liver fatty acid binding protein (L-FABP) of rat liver cytosol. In search for the roles of L-FABP in hepatocytes, we previously stably transfected rat L-FABP sense and antisense cDNAs into rat hepatom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad601e6aeb1f07bd19d3a0f26336352
https://doi.org/10.1002/jcp.1041570105
https://doi.org/10.1002/jcp.1041570105
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374305
In recent years, multiple associations have linked induced cell proliferation (mitogenesis) of rat hepatocytes to liver fatty acid binding protein (L-FABP), a cytoplasmic 14 kDa protein previously termed Z protein. The protein was formerly thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316a65d866cd965bfdc42cdc3d33f902
https://doi.org/10.1007/978-1-4615-5325-0_70
https://doi.org/10.1007/978-1-4615-5325-0_70
Publikováno v:
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury ISBN: 9781461365624
Growth inhibition is generally an early event during chemical carcinogenesis (1). The effect is to confine the proliferation of the escaping chemically transformed cells to regions of focal hyperplasia among the growth suppressed non-transformed cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f825ba49fca1f3646278f3309c2fb9
https://doi.org/10.1007/978-1-4615-3520-1_86
https://doi.org/10.1007/978-1-4615-3520-1_86
The hepatic carcinogen N-2-fluorenylacetamide (2-acetylaminofluorene) was shown previously to interact specifically with its target protein, liver fatty acid binding protein (L-FABP), early during hepatocarcinogenesis in rats. In search of the signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ac1ba6e97a188e47ba45b8a86c58b5
https://europepmc.org/articles/PMC49181/
https://europepmc.org/articles/PMC49181/
Autor:
Shahid H. Khan, Sam Sorof
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(23)
Liver fatty acid binding protein (L-FABP) is the principal target protein of the hepatic carcinogen N-(2-fluorenyl)acetamide (2-acetylaminofluorene) in rat liver. In addition, the cyclopentenone prostaglandins (PG), PGA, PGJ2, and delta 12-PGJ2, inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c547a6bc8cc51f0e46f9f531bd6a41bd
https://pubmed.ncbi.nlm.nih.gov/2251282
https://pubmed.ncbi.nlm.nih.gov/2251282
Autor:
Sam Sorof, Quentin J. Tonelli
Publikováno v:
Differentiation. 22:195-200
In order to reduce cellular complexity in the study of the controls of the biochemical differentiation of mammary gland epithelium, approximately 100-fold purified epithelial cells from the mammary glands of virgin BALB/c mice were grown in three-dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf944a11af36541c9f39ef41c8e52daf
https://doi.org/10.1111/j.1432-0436.1982.tb01250.x
https://doi.org/10.1111/j.1432-0436.1982.tb01250.x
Publikováno v:
JNCI: Journal of the National Cancer Institute. 72:185-189
The preneoplastic state is without apparent effect on the induction or prevention of epidermidalization in transplanted mammary outgrowth lines. Development of squamous metaplasia and differentiation (keratinization) were induced in organ cultures of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87e40359e8e4059e78c94c59ae1ca904
https://doi.org/10.1093/jnci/72.1.185
https://doi.org/10.1093/jnci/72.1.185
Publikováno v:
Differentiation. 20:260-263
The present study tests the hypothesis that agents known to elevate the level of intracellular cyclic adenine nucleotide may direct different epithelial cells onto a pathway of epidermoid (squamous) development and differentiation. We report here tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cb9afc40c7d9d9209b263f2d7874fe
https://doi.org/10.1111/j.1432-0436.1981.tb01181.x
https://doi.org/10.1111/j.1432-0436.1981.tb01181.x