Assessing women's preferences towards tests that may reveal uncertain results from prenatal genomic testing: Development of attributes for a discrete choice experiment, using a mixed-methods design.

Autor: Jennifer Hammond, Jasmijn E Klapwijk, Sam Riedijk, Stina Lou, Kelly E Ormond, Ida Vogel, Lisa Hui, Emma-Jane Sziepe, James Buchanan, Charlotta Ingvoldstad-Malmgren, Maria Johansson Soller, Eleanor Harding, Melissa Hill, Celine Lewis

Publikováno v: PLoS ONE, Vol 17, Iss 1, p e0261898 (2022)

Prenatal DNA tests, such as chromosomal microarray analysis or exome sequencing, increase the likelihood of receiving a diagnosis when fetal structural anomalies are identified. However, some parents will receive uncertain results such as variants of

Externí odkaz: https://doaj.org/article/9d1157129095401b99b936452baba713

Changes in opinions about human germline gene editing as a result of the Dutch DNA-dialogue project

Autor: Diewertje Houtman, Boy Vijlbrief, Marike Polak, Jacqueline Pot, Petra Verhoef, Martina Cornel, Sam Riedijk

Publikováno v: European Journal of Human Genetics. Nature Publishing Group
European Journal of Human Genetics, 31(4), 409-416. Nature Publishing Group
Houtman, D, Vijlbrief, B, Polak, M, Pot, J, Verhoef, P, Cornel, M & Riedijk, S 2022, ' Changes in opinions about human germline gene editing as a result of the Dutch DNA-dialogue project ', European Journal of Human Genetics . https://doi.org/10.1038/s41431-022-01114-w

Public engagement for Human Germline Genome Editing (HGGE) has often been called for, for example by the WHO. However, the impact of public engagement remains largely unknown. This study reports on public engagement outcomes in the context of a publi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bde4760ea634926737a20f4a63b3cf
http://www.scopus.com/inward/record.url?scp=85129837017&partnerID=8YFLogxK

Dealing with uncertain results from chromosomal microarray and exome sequencing in the prenatal setting: An international cross‐sectional study with healthcare professionals

Autor: Kelly E. Ormond, Mahesh Choolani, Melissa Hill, Celine Lewis, Jennifer Hammond, Ida Vogel, Stina Lou, Sam Riedijk, Charlotta Ingvoldstad-Malmgren, Lisa Hui, Jasmijn E. Klapwijk, Emma Jane Szepe, Eleanor Harding, Maria Johansson Soller

Publikováno v: Lewis, C, Hammond, J, Klapwijk, J E, Harding, E, Lou, S, Vogel, I, Szepe, E J, Hui, L, Ingvoldstad-Malmgren, C, Soller, M J, Ormond, K E, Choolani, M, Hill, M & Riedijk, S 2021, ' Dealing with uncertain results from chromosomal microarray and exome sequencing in the prenatal setting : an international cross-sectional study with healthcare professionals ', Prenatal Diagnosis, vol. 41, no. 6, pp. 720-732 . https://doi.org/10.1002/pd.5932
Prenatal Diagnosis, 41(6), 720-732. John Wiley and Sons Ltd
Lewis, C, Hammond, J, Klapwijk, J E, Harding, E, Lou, S, Vogel, I, Szepe, E J, Hui, L, Ingvoldstad-Malmgren, C, Soller, M J, Ormond, K E, Choolani, M, Hill, M & Riedijk, S 2021, ' Dealing with uncertain results from chromosomal microarray and exome sequencing in the prenatal setting : An international cross-sectional study with healthcare professionals ', Prenatal Diagnosis, vol. 41, no. 6, pp. 720-732 . https://doi.org/10.1002/pd.5932
Prenatal Diagnosis
Prenatal Diagnosis, 41(6), 720-732. John Wiley & Sons Ltd.

Objectives To conduct qualitative interviews with healthcare providers working in different countries to understand their experiences of dealing with uncertain results from prenatal chromosome microarray analysis (CMA) and exome sequencing (ES). Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e62a24407ba5ff20aa0192722b8c4f3
https://doi.org/10.1002/pd.5932

Factor's that impact on women's decision-making around prenatal genomic tests: An international discrete choice survey

Autor: James Buchanan, Melissa Hill, Caroline M. Vass, Jennifer Hammond, Sam Riedijk, Jasmijn E. Klapwijk, Eleanor Harding, Stina Lou, Ida Vogel, Lisa Hui, Charlotta Ingvoldstad‐Malmgren, Maria Johansson Soller, Kelly E. Ormond, Mahesh Choolani, Qian Zheng, Lyn S. Chitty, Celine Lewis

Publikováno v: Prenatal Diagnosis, 42 (7)
Buchanan, J, Hill, M, Vass, C M, Hammond, J, Riedijk, S, Klapwijk, J E, Harding, E, Lou, S, Vogel, I, Hui, L, Ingvoldstad-Malmgren, C, Soller, M J, Ormond, K E, Choolani, M, Zheng, Q, Chitty, L S & Lewis, C 2022, ' Factor's that impact on women's decision-making around prenatal genomic tests : An international discrete choice survey ', Prenatal Diagnosis, vol. 42, no. 7 . https://doi.org/10.1002/pd.6159
Prenatal Diagnosis, 42(7), 934-946. John Wiley & Sons Ltd.
Buchanan, J, Hill, M, Vass, C M, Hammond, J, Riedijk, S, Klapwijk, J E, Harding, E, Lou, S, Vogel, I, Hui, L, Ingvoldstad-Malmgren, C, Soller, M J, Ormond, K E, Choolani, M, Zheng, Q, Chitty, L S & Lewis, C 2022, ' Factor's that impact on women's decision-making around prenatal genomic tests : An international discrete choice survey ', Prenatal Diagnosis, vol. 42, no. 7, pp. 934-946 . https://doi.org/10.1002/pd.6159
Prenatal Diagnosis, 42(7), 934-946. John Wiley and Sons Ltd

Objective We conducted a survey-based discrete-choice experiment (DCE) to understand the test features that drive women's preferences for prenatal genomic testing, and explore variation across countries. Methods Five test attributes were identified a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab42b5bce4f79c6cad2637717c75ed9

The iterative process of decision-making

Autor: Sam Riedijk, Frederike Dekkers, Lara Ras, Jane Fisher, Eva Pajkrt, Liesbeth van Leeuwen, Iris Emons, Karin E.M. Diderich

Publikováno v: Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty, 121-135
STARTPAGE=121;ENDPAGE=135;TITLE=Prenatal Genetic Counseling
Riedijk, S, Dekkers, F, Ras, L, Emons, I, Fisher, J, Pajkrt, E, van Leeuwen, L & Diderich, K E M 2022, The iterative process of decision-making . in Prenatal Genetic Counseling : Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty . Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty, Elsevier, pp. 121-135 . https://doi.org/10.1016/B978-0-12-823329-0.00004-0

This is the timeframe during which couples hear the (most likely) diagnosis and have to make the decision to terminate or continue the pregnancy. This timeframe is often very short. During the course of only a few weeks, couples see a large number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563d2c18f15a56157277d661869e25b9
https://doi.org/10.1016/b978-0-12-823329-0.00004-0