Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sam P. Nayler"'
Autor:
Sam P. Nayler, Joseph E. Powell, Darya P. Vanichkina, Othmar Korn, Christine A. Wells, Refik Kanjhan, Jian Sun, Ryan J. Taft, Martin F. Lavin, Ernst J. Wolvetang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Ataxia-telangiectasia (A-T) is a rare genetic disorder caused by loss of function of the ataxia-telangiectasia-mutated kinase and is characterized by a predisposition to cancer, pulmonary disease, immune deficiency and progressive degeneration of the
Externí odkaz:
https://doaj.org/article/17a53e9a51964d62b225ea5908976ddc
Autor:
James R. Krycer, Sam P. Nayler
Publikováno v:
The Cerebellum. 21:838-850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f3626a5c29ba26ee7d4ffbcce1fef9
https://doi.org/10.1007/s12311-022-01415-2
https://doi.org/10.1007/s12311-022-01415-2
Autor:
Irina Vetter, Patrick R.J. Fortuna, Frank Rigo, Leonard Lipovich, Sam P Nayler, Glória Regina Franco, Dong Soo Lee, Jesper L.V. Maag, Seth Blackshaw, Victoria M. Warn, James Briggs, Guy Barry, Erin M. Singh, Ernst J. Wolvetang, Fabien Dachet, Jeffrey A. Loeb, Lotta Avesson, Luis Arriola-Martinez, Nicky Jonkhout, Do Won Hwang, John S. Mattick, Terence J. O'Brien, Marcel E. Dinger, Margaret J. Morris, Jianfei Hu, Dominik C. Kaczorowski, Pieter Mestdagh, Nigel C. Jones, Andrew Gong, Ezgi Ozturk
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports
Despite their abundance, the molecular functions of long non-coding RNAs in mammalian nervous systems remain poorly understood. Here we show that the long non-coding RNA, NEAT1, directly modulates neuronal excitability and is associated with patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efb20e968fc071196428223c1dfe99d
https://doi.org/10.1038/srep40127
https://doi.org/10.1038/srep40127
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969531
Reprogramming of cells enables generation of pluripotent stem cells and resulting progeny through directed differentiation, making this technology an invaluable tool for the study of human development and disease. Reprogramming occurs with a wide ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae30a29e9297ea4f17228795f15190b
https://doi.org/10.1007/978-1-4939-6955-5_29
https://doi.org/10.1007/978-1-4939-6955-5_29
Autor:
Jessica C. Mar, Ernst J. Wolvetang, Martin F. Lavin, Magtouf Gatei, Christine A. Wells, Richard A. Gatti, Sergei Kozlov, Sam P Nayler
Publikováno v:
Stem Cells Translational Medicine. 1:523-535
Pluripotent stem cells can differentiate into every cell type of the human body. Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) therefore provides an opportunity to gain insight into the molecular and cellular basis of dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6178eebda32c851ca03992419a65f3c
https://doi.org/10.5966/sctm.2012-0024
https://doi.org/10.5966/sctm.2012-0024
Autor:
Giuseppe De Michele, Jane Sun, Martin F. Lavin, Brent L. Fogel, Chiara Criscuolo, Sam P Nayler, Olivier J. Becherel, Giovanni Coppola, Ernst J. Wolvetang, Fuying Gao, Abrey J. Yeo
Publikováno v:
Human molecular genetics. 24(20)
Ataxia oculomotor apraxia type 2 (AOA2) is a rare autosomal recessive cerebellar ataxia. Recent evidence suggests that the protein defective in this syndrome, senataxin (SETX), functions in RNA processing to protect the integrity of the genome. To da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1696f3e4be0aad4ea94e5835c295117
https://pubmed.ncbi.nlm.nih.gov/26231220
https://pubmed.ncbi.nlm.nih.gov/26231220
Autor:
Seth Blackshaw, James Briggs, Katia Nones, Frank Rigo, Guy Barry, Timothy W. Bredy, John S. Mattick, Murray J. Cairns, Vikram S. Ratnu, Ryan J. Taft, Erin M. Poth, Ernst J. Wolvetang, Sam P Nayler, Shinichi Nakagawa, Natalie J. Beveridge, Jianfei Hu, Darya P. Vanichkina
Publikováno v:
Molecular psychiatry. 19(4)
Schizophrenia (SZ) is a complex disease characterized by impaired neuronal functioning. Although defective alternative splicing has been linked to SZ, the molecular mechanisms responsible are unknown. Additionally, there is limited understanding of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf5f00434b53f46204515ede2e947dd
https://pubmed.ncbi.nlm.nih.gov/23628989
https://pubmed.ncbi.nlm.nih.gov/23628989