Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sam O. Hofman"'
Autor:
Erica M. Pasini, Annemarie Voorberg van der Wel, Nicole Heijmans, Onny Klop, Anne-Marie Zeeman, Herman Oostermeijer, Ivonne Nieuwenhuis, Roberto Rodriguez Garcia, Nicole Onur van der Werff, Sam O. Hofman, Frank A. W. Verreck, Edmond J. Remarque, Bart W. Faber, Clemens H. M. Kocken
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract Vaccine development for Plasmodium vivax, an important human relapsing malaria, is lagging behind. In the case of the most deadly human malaria P. falciparum, unprecedented high levels of protection have been obtained by immunization with li
Externí odkaz:
https://doaj.org/article/2a1a9ec4e08c40a986eb4783af38d801
Autor:
Karin Dijkman, Richard A. W. Vervenne, Claudia C. Sombroek, Charelle Boot, Sam O. Hofman, Krista E. van Meijgaarden, Tom H. M. Ottenhoff, Clemens H. M. Kocken, Krista G. Haanstra, Michel P. M. Vierboom, Frank A. W. Verreck
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
While tuberculosis continues to afflict mankind, the immunological mechanisms underlying TB disease development are still incompletely understood. Advanced preclinical models for TB research include both rhesus and cynomolgus macaques (Macaca mulatta
Externí odkaz:
https://doaj.org/article/60dd21741d194b77915749c68bee85a6
Autor:
Gerrit Koopman, Daniella Mortier, Petra Mooij, Ernst J. Verschoor, Edmond J. Remarque, Willy M. J. M. Bogers, Zahra Fagrouch, Samira Michels, Sam O. Hofman
Publikováno v:
Journal of General Virology. 100:738-751
Antibodies directed against the conserved regions within the influenza A haemagglutinin (HA) protein are detected at low frequency in humans. These antibodies display a broad reactivity against divergent influenza virus strains and could potentially
Autor:
Krista G. Haanstra, Chantal Hoffmann, Aurelio Bonavia, Patricia A. Darrah, Stéphane Leung-Theung-Long, H. Jacob Borish, Dominick Laddy, Robert A. Seder, Danilo R. Casimiro, Frank A. W. Verreck, Claudia C. Sombroek, Charelle Boot, Nathalie Silvestre, Mary Limbach, Geneviève Inchauspé, Richard A. W. Vervenne, Alexander G. White, Karin Dijkman, Mohamed A Khayum, Michel P.M. Vierboom, Doris Schmitt, Marieke A. Stammes, Maria Lempicki, Nadia Ouaked, Ravi Anantha, Sam O. Hofman, Agnes L Chenine, Thomas G. Evans
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-12 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-12 (2020)
Tuberculosis (TB) still is the principal cause of death from infectious disease and improved vaccination strategies are required to reduce the disease burden and break TB transmission. Here, we investigated different routes of administration of vecto
Autor:
Sam O. Hofman, Tom H. M. Ottenhoff, Richard A. W. Vervenne, Frank A. W. Verreck, Krista G. Haanstra, Clemens H. M. Kocken, Karin Dijkman, Michel P.M. Vierboom, Claudia C. Sombroek, Charelle Boot, Krista E. van Meijgaarden
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 10
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 10
Frontiers in Immunology, Vol 10 (2019)
While tuberculosis continues to afflict mankind, the immunological mechanisms underlying TB disease development are still incompletely understood. Advanced preclinical models for TB research include both rhesus and cynomolgus macaques (Macaca mulatta
Autor:
Jan A.M. Langermans, Sam O. Hofman, Ingrid H.C.H.M. Philippens, Sigrid K. Franke, Jacqueline Wubben
Publikováno v:
Scientific Reports, 9:880, 1-9. Nature Publishing Group
Scientific Reports
Scientific Reports, 9(1). NLM (Medline)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Philippens, I H C H M, Wubben, J A, Franke, S K, Hofman, S & Langermans, J A M 2019, ' Involvement of the Red Nucleus in the Compensation of Parkinsonism may Explain why Primates can develop Stable Parkinson’s Disease ', Scientific Reports, vol. 9, 880, pp. 1-9 . https://doi.org/10.1038/s41598-018-37381-1
Scientific Reports
Scientific Reports, 9(1). NLM (Medline)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Philippens, I H C H M, Wubben, J A, Franke, S K, Hofman, S & Langermans, J A M 2019, ' Involvement of the Red Nucleus in the Compensation of Parkinsonism may Explain why Primates can develop Stable Parkinson’s Disease ', Scientific Reports, vol. 9, 880, pp. 1-9 . https://doi.org/10.1038/s41598-018-37381-1
Neurological compensatory mechanisms help our brain to adjust to neurodegeneration as in Parkinson’s disease. It is suggested that the compensation of the damaged striato-thalamo-cortical circuit is focused on the intact thalamo-rubro-cerebellar pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae090b2248635460ea4d302005f1399c
https://research.vu.nl/en/publications/1ece4d82-5f1b-4609-8fd6-35bfdddf40f8
https://research.vu.nl/en/publications/1ece4d82-5f1b-4609-8fd6-35bfdddf40f8
Autor:
Thierry T. Diagana, Florian Nigsch, Tewis Bouwmeester, Els J. Klooster, Binesh Shrestha, Guglielmo Roma, Erika L. Flannery, Sven Schuierer, Anne-Marie Zeeman, Jetsumon Sattabongkot, Vorada Chuenchob, Niwat Kangwanrangsan, Annemarie Voorberg-van der Wel, Walter Carbone, Devendra Kumar Gupta, Nicole L Bertschi, Ivonne G. Nieuwenhuis, Bart W. Faber, Martin Beibel, Clemens H. M. Kocken, Nicole van der Werff, Sebastian A. Mikolajczak, Judith Knehr, Sam O. Hofman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43497f241e189e0f046e41d97c2dac8f
https://doi.org/10.7554/elife.41081.025
https://doi.org/10.7554/elife.41081.025
Autor:
Florian Nigsch, Thierry T. Diagana, Els J. Klooster, Devendra Kumar Gupta, Tewis Bouwmeester, Bart W. Faber, Guglielmo Roma, Binesh Shrestha, Anne-Marie Zeeman, Niwat Kangwanrangsan, Vorada Chuenchob, Judith Knehr, Sven Schuierer, Sebastian A. Mikolajczak, Erika L. Flannery, Nicole L Bertschi, Walter Carbone, Ivonne G. Nieuwenhuis, Jetsumon Sattabongkot, Sam O. Hofman, Martin Beibel, Nicole van der Werff, Annemarie Voorberg-van der Wel, Clemens H. M. Kocken
Publikováno v:
eLife, Vol 7 (2018)
Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts. New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite biology impedes drug discovery. We previously unraveled the transcriptome
Autor:
Sam O. Hofman, Eugenia Puentes, Clemens H. M. Kocken, Joost H.A. Martens, Nacho Aguilo, Frank A. W. Verreck, Liesbeth van Emst, Esteban M. Rodríguez, Krista G. Haanstra, Simone J.C.F.M. Moorlag, Reinout van Crevel, Jorge Domínguez-Andrés, Richard A. W. Vervenne, Maarten van der Sande, Michel P.M. Vierboom, Carlos Martin, Jelle Thole, Claudia C. Sombroek, Charelle Boot, Karin Dijkman, Mihai G. Netea
Publikováno v:
Cell Reports Medicine, 2, 1
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Cell Rep Med.
Cell Reports Medicine
Cell Reports Medicine, 2
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Cell Rep Med.
Cell Reports Medicine
Cell Reports Medicine, 2
Summary BCG vaccination can strengthen protection against pathogens through the induction of epigenetic and metabolic reprogramming of innate immune cells, a process called trained immunity. We and others recently demonstrated that mucosal or intrave
Autor:
August B. Smit, Sam O. Hofman, Ronald E. van Kesteren, Sigrid K. Franke, Jacqueline Wubben, Ingrid H.C.H.M. Philippens
Publikováno v:
van Kesteren, R E, Hofman, S, Wubben, J A M, Smit, A B & Philippens, I H C H M 2016, ' Individual and Familial Susceptibility to MPTP in a Common Marmoset Model for Parkinson's Disease ', Neurodegenerative Diseases, vol. 16, no. 5-6, pp. 293-303 . https://doi.org/10.1159/000442574
Neurodegenerative Diseases, 16(5-6), 293-303. S. Karger AG
Neurodegenerative Diseases, 16(5-6), 293-303. S. Karger AG
Introduction: Insight into susceptibility mechanisms underlying Parkinson's disease (PD) would aid the understanding of disease etiology, enable target finding and benefit the development of more refined disease-modifying strategies. Methods: We used