Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sam Nichols"'
Autor:
Robin M. Delaine-Smith, Eleni Maniati, Beatrice Malacrida, Sam Nichols, Reza Roozitalab, Roanne R. Jones, Laura S.M. Lecker, Oliver M.T. Pearce, Martin M. Knight, Frances R. Balkwill
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102674- (2021)
Summary: In a multi-level “deconstruction” of omental metastases, we previously identified a prognostic matrisome gene expression signature in high-grade serous ovarian cancer (HGSOC) and twelve other malignancies. Here, our aim was to understand
Externí odkaz:
https://doaj.org/article/6068ad32821044adbec1edf7e797e977
Autor:
Beatrice Malacrida, Sam Nichols, Eleni Maniati, Roanne Jones, Robin Delanie-Smith, Reza Roozitalab, Eleanor J. Tyler, Morgan Thomas, Gina Boot, Jonas Mackerodt, Michelle Lockley, Martin M. Knight, Frances R. Balkwill, Oliver M.T. Pearce
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102676- (2021)
Summary: Guided by a multi-level “deconstruction” of omental metastases, we developed a tetra (four cell)-culture model of primary human mesothelial cells, fibroblasts, adipocytes, and high-grade serous ovarian cancer (HGSOC) cell lines. This mul
Externí odkaz:
https://doaj.org/article/99a346004e8b4e63bd0a6643a5d15ba8
Autor:
Frances R. Balkwill, Martin M. Knight, Conrad Bessant, Michelle Lockley, Pedro R. Cutillas, Claude Chelala, James D. Brenton, John Connelly, Benjamin G. Vincent, Jonathan S. Serody, Hemant M. Kocher, J. Louise Jones, John Gribben, Tom Dowe, Anne Montfort, Roanne R. Jones, Probir Chakravarty, Dayem Ullah, Vinothini Rajeeve, Steffen Böhm, Jun Wang, Sam Nichols, Eleni Maniati, Robin M. Delaine-Smith, Oliver M.T. Pearce
Supplementary Tables 10 - 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5704d6479ac7ef1a7815adffb7d4a32b
https://doi.org/10.1158/2159-8290.22532215
https://doi.org/10.1158/2159-8290.22532215
Autor:
Frances R. Balkwill, Martin M. Knight, Conrad Bessant, Michelle Lockley, Pedro R. Cutillas, Claude Chelala, James D. Brenton, John Connelly, Benjamin G. Vincent, Jonathan S. Serody, Hemant M. Kocher, J. Louise Jones, John Gribben, Tom Dowe, Anne Montfort, Roanne R. Jones, Probir Chakravarty, Dayem Ullah, Vinothini Rajeeve, Steffen Böhm, Jun Wang, Sam Nichols, Eleni Maniati, Robin M. Delaine-Smith, Oliver M.T. Pearce
Supplemental Figures and Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57acd1aa72bbb01ca068adf24c1188c6
https://doi.org/10.1158/2159-8290.22532221
https://doi.org/10.1158/2159-8290.22532221
Autor:
Frances R. Balkwill, Martin M. Knight, Conrad Bessant, Michelle Lockley, Pedro R. Cutillas, Claude Chelala, James D. Brenton, John Connelly, Benjamin G. Vincent, Jonathan S. Serody, Hemant M. Kocher, J. Louise Jones, John Gribben, Tom Dowe, Anne Montfort, Roanne R. Jones, Probir Chakravarty, Dayem Ullah, Vinothini Rajeeve, Steffen Böhm, Jun Wang, Sam Nichols, Eleni Maniati, Robin M. Delaine-Smith, Oliver M.T. Pearce
Supplementary Tables 15 - 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e52ccbe5c6d25b21cd45f9d7c6f605
https://doi.org/10.1158/2159-8290.22532212.v1
https://doi.org/10.1158/2159-8290.22532212.v1
Autor:
Frances R. Balkwill, Martin M. Knight, Conrad Bessant, Michelle Lockley, Pedro R. Cutillas, Claude Chelala, James D. Brenton, John Connelly, Benjamin G. Vincent, Jonathan S. Serody, Hemant M. Kocher, J. Louise Jones, John Gribben, Tom Dowe, Anne Montfort, Roanne R. Jones, Probir Chakravarty, Dayem Ullah, Vinothini Rajeeve, Steffen Böhm, Jun Wang, Sam Nichols, Eleni Maniati, Robin M. Delaine-Smith, Oliver M.T. Pearce
Supplementary Tables 4 - 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5fd343d1917542ef28f72a111c4f08
https://doi.org/10.1158/2159-8290.22532209.v1
https://doi.org/10.1158/2159-8290.22532209.v1
Autor:
Frances R. Balkwill, Martin M. Knight, Conrad Bessant, Michelle Lockley, Pedro R. Cutillas, Claude Chelala, James D. Brenton, John Connelly, Benjamin G. Vincent, Jonathan S. Serody, Hemant M. Kocher, J. Louise Jones, John Gribben, Tom Dowe, Anne Montfort, Roanne R. Jones, Probir Chakravarty, Dayem Ullah, Vinothini Rajeeve, Steffen Böhm, Jun Wang, Sam Nichols, Eleni Maniati, Robin M. Delaine-Smith, Oliver M.T. Pearce
Supplementary Tables 1 - 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99964d0cca7a259345fae0cceab6408d
https://doi.org/10.1158/2159-8290.22532218.v1
https://doi.org/10.1158/2159-8290.22532218.v1
Autor:
Reza Roozitalab, Roanne R. Jones, Oliver M. T. Pearce, Beatrice Malacrida, Sam Nichols, Laura S.M. Lecker, Frances R. Balkwill, Robin M. Delaine-Smith, Eleni Maniati, Martin M. Knight
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102674-(2021)
iScience
iScience
Summary In a multi-level “deconstruction” of omental metastases, we previously identified a prognostic matrisome gene expression signature in high-grade serous ovarian cancer (HGSOC) and twelve other malignancies. Here, our aim was to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077fcbd9aa2de37df67d3c0c5ef5772f
https://doi.org/10.1101/2021.02.01.428374
https://doi.org/10.1101/2021.02.01.428374
Autor:
Robin M. Delaine-Smith, Martin M. Knight, Beatrice Malacrida, Roanne L. Jones, Eleni Maniati, Oliver M. T. Pearce, Frances R. Balkwill, Sam Nichols
Publikováno v:
Cancer Research. 81:2642-2642
Studying the complexity of the tumor microenvironment (TME) still represents a challenge in research. The intricate communication within the stroma - fibroblast, immune cells, endothelial cells and the extracellular matrix (ECM) - and the malignant c
Autor:
Steffen Böhm, Michelle Lockley, Jun Wang, Hemant M. Kocher, John G. Gribben, Claude Chelala, James D. Brenton, Pedro R. Cutillas, Robin M. Delaine-Smith, Benjamin G. Vincent, John T. Connelly, Martin M. Knight, Sam Nichols, Probir Chakravarty, Dayem Ullah, Roanne R. Jones, Vinothini Rajeeve, Conrad Bessant, Tom Dowe, Eleni Maniati, Anne Montfort, Oliver M. T. Pearce, Jonathan S. Serody, Frances R. Balkwill, J. Louise Jones
Publikováno v:
Cancer discovery. 8(3)
We have profiled, for the first time, an evolving human metastatic microenvironment by measuring gene expression, matrisome proteomics, cytokine and chemokine levels, cellularity, extracellular matrix organization, and biomechanical properties, all o