Výsledky vyhledávání - "Sam McFadden"

Sexual Dimorphic Metabolic and Cognitive Responses of C57BL/6 Mice to Fisetin or Dasatinib and Quercetin Cocktail Oral Treatment

Autor: Andrzej Bartke, Kathleen Quinn, Kevin N. Hascup, Robert Stockwell, Yimin Fang, Mackenzie R. Peck, Sam McFadden, Erin R. Hascup, David Medina

Senolytic treatment in aged mice clears senescent cell burden leading to functional improvements. However, less is known regarding the effects of these compounds when administered prior to significant senescent cell accumulation. From 4-13 months of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68f698fa6c8d0721b1a6a1cbf0e1289c
https://doi.org/10.1101/2021.11.08.467509

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Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient

Autor: Sam McFadden, Andrzej Bartke, Yimin Fang, Cristal M. Hill, Liou Y. Sun, Justin Darcy

Publikováno v: Experimental Biology and Medicine. 241:1764-1771

Ames dwarf mice are exceptionally long-lived due to a Prop1 loss of function mutation resulting in deficiency of growth hormone, thyroid-stimulating hormone and prolactin. Deficiency in thyroid-stimulating hormone and growth hormone leads to greatly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf46d5bf6b1c02d55da122a73e940718
https://doi.org/10.1177/1535370216650292

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