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of 6
pro vyhledávání: '"Sam M. Rowe"'
Autor:
Dawei Guo, Himansha Singh, Atsushi Shimoyama, Charlotte Guffick, Yakun Tang, Sam M. Rowe, Timothy Noel, David R. Spring, Koichi Fukase, Hendrik W. van Veen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Guo et al. conduct a biochemical analysis of the energy dependence of substrate transport by MsbA, an essential ABC lipid transporter in Gram-negative bacteria. The authors examine the flopping of physiologically relevant lipids by MsbA and their dif
Externí odkaz:
https://doaj.org/article/0d842e3c3c1149e0b79ed577d405c570
Publikováno v:
Chemical Society Reviews
Bacterial infections caused by ‘superbugs’ are increasing globally, and conventional antibiotics are becoming less effective against these bacteria, such that we risk entering a post-antibiotic era. In recent years, antimicrobial peptides (AMPs)
Publikováno v:
Chemical Society Reviews. 51:792-792
Correction for ‘The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions’ by Bee Ha Gan et al., Chem. Soc. Rev., 2021, 50, 7820–7880, DOI: 10.1039/D0CS00729C.
Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling
Autor:
Hannah F. Sore, Jeremy S. Parker, Elaine Fowler, Naomi Robertson, Sam M. Rowe, Stephen J. Walsh, David R. Spring, Yuteng Wu, M. Yoshida
Publikováno v:
Chemical communications (Cambridge, England). 55(64)
We report a novel divinyltriazine linker for the stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The stapling reaction occurred rapidly under mild conditions on a range of unprotected peptide
Autor:
Paul M. Roberts, Marek Buchman, Kristína Csatayová, Ai M. Fletcher, Stephen G. Davies, Sam M. Rowe, James E. Thomson, Ian T. T. Houlsby
Publikováno v:
ChemInform. 47
Efficient de novo asymmetric syntheses of (+)-preussin B, the C(2)-epimer of (−)-preussin B, and 3-deoxy-(+)-preussin B have been developed, using the diastereoselective conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to tert-bu
Autor:
Ian T. T. Houlsby, Sam M. Rowe, Ai M. Fletcher, Marek Buchman, James E. Thomson, Kristína Csatayová, Stephen G. Davies, Paul M. Roberts
Publikováno v:
Journal of Organic Chemistry. 81(12)
Efficient de novo asymmetric syntheses of (+)-preussin B, the C(2)-epimer of (-)-preussin B, and 3-deoxy-(+)-preussin B have been developed, using the diastereoselective conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to tert-buty