Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sam M Hanash"'
Autor:
Rina M. Mbofung, Jodi A. McKenzie, Shruti Malu, Min Zhang, Weiyi Peng, Chengwen Liu, Isere Kuiatse, Trang Tieu, Leila Williams, Seram Devi, Emily Ashkin, Chunyu Xu, Lu Huang, Minying Zhang, Amjad H. Talukder, Satyendra C. Tripathi, Hiep Khong, Nikunj Satani, Florian L. Muller, Jason Roszik, Timothy Heffernan, James P. Allison, Gregory Lizee, Sam M. Hanash, David Proia, Rodabe Amaria, R. Eric Davis, Patrick Hwu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Many patients fail to respond to T cell based immunotherapies. Here, the authors, through a high-throughput screening, identify HSP90 inhibitors as a class of preferred drugs for treatment combination with immunotherapy.
Externí odkaz:
https://doaj.org/article/51b2a4e16a0b435cabee2477f3975980
Autor:
Johannes F. Fahrmann, Amanda R. Wasylishen, Carolina R.C. Pieterman, Ehsan Irajizad, Jody Vykoukal, Ranran Wu, Jennifer D. Dennison, Christine B. Peterson, Guillermina Lozano, Hua Zhao, Kim-Ahn Do, Daniel M. Halperin, Sunita K. Agarwal, Jenny E. Blau, Jaydira D. Rivero, Naris Nilubol, Mary F. Walter, James M. Welch, Lee S. Weinstein, Menno R. Vriens, Rachel S. van Leeuwaarde, Mark J.C. van Treijen, Gerlof D. Valk, Nancy D. Perrier, Sam M Hanash, Hiroyuki Katayama
Publikováno v:
Cancer Prevention Research. 16:P066-P066
Multiple Endocine Neoplasia Type 1 (MEN1) is associated with duodenopancreatic neuroendocrine tumors (dpNETs) and metastatic dpNET is the primary cause of disease-related mortality for this condition. Currently, there is a paucity of prognostic facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4de1043cd7abf43916322168de91dd1
https://doi.org/10.1158/1940-6215.precprev22-p066
https://doi.org/10.1158/1940-6215.precprev22-p066
Autor:
Reinhard Ullmann, Christa Fonatsch, Sam M. Hanash, Susanne Schnittger, Andrea Zatkova, Claudia Schoch, Barbara J. Lamb, Rork Kuick, Jean Marie Rouillard, Katharina Wimmer
Publikováno v:
Genes, Chromosomes and Cancer. 39:263-276
Amplification within chromosome arm 11q involving the mixed-lineage leukemia gene (MLL) locus is a rare but recurrent aberration in acute myeloid leukemia and myelodysplastic syndrome (AML/MDS). We and others have observed that 11q amplifications in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236d8716bfebb38e1ddc97d042279c57
https://doi.org/10.1002/gcc.20002
https://doi.org/10.1002/gcc.20002
Publikováno v:
Leukemia. 16:478-485
Although most drugs target proteins, the proteome has remained largely untapped for the discovery of drug targets. The sequencing of the human genome has had a tremendous impact on proteomics and has provided a framework for protein identification. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06c92a6d07fd83a2acfb324d56159c3
https://doi.org/10.1038/sj.leu.2402412
https://doi.org/10.1038/sj.leu.2402412
Autor:
Barbara J. Lamb, Rork Kuick, Peter F. Ambros, Markus Eckart, Andreas Weinhäusl, Xiao-Xiang Zhu, Katharina Wimmer, Jean Marie Rouillard, Christa Fonatsch, Sam M. Hanash
Publikováno v:
Genes, Chromosomes and Cancer. 33:285-294
Restriction landmark genome scanning (RLGS) allows comparative analysis of several thousand DNA fragments in the genome and provides a means to identify CpG islands that are altered in tumor cells as a result of amplification, deletion, or methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96bb6b831081f003d379c2a0f18ee6af
https://doi.org/10.1002/gcc.10030
https://doi.org/10.1002/gcc.10030
Publikováno v:
PROTEOMICS. 1:1279-1287
A novel proteomic approach for probing cell and tissue proteome, which combines liquid phase protein separations with microarray technology has been developed. Proteins in cell and tissue lysates or in cellular subfractions are separated using any on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d214d286052d186f37638a680191cae
https://doi.org/10.1002/1615-9861(200110)1:10<1279::aid-prot1279>3.0.co
https://doi.org/10.1002/1615-9861(200110)1:10<1279::aid-prot1279>3.0.co
Publikováno v:
Clinical Chemistry. 47:1901-1911
Early detection is critical in cancer control and prevention. Biomarkers help in this process by providing valuable information about a the status of a cell at any given point in time. As a cell transforms from nondiseased to neoplastic, distinct cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09a1a550cd634cfe785b12e7323edefa
https://doi.org/10.1093/clinchem/47.10.1901
https://doi.org/10.1093/clinchem/47.10.1901
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:1907-1916
Protein spots from two-dimensional (2-D) gel electrophoresis of a human erythroleukemia cell line have been identified by analysis of the in-gel tryptic digests using capillary high performance liquid chromatography (HPLC) separation with on-line det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448542346cbcbfc67dec0ded500b1563
https://doi.org/10.1002/(sici)1097-0231(19991015)13:19<1907::aid-rcm732>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19991015)13:19<1907::aid-rcm732>3.0.co
Autor:
David R. Keim, Sam M. Hanash
Publikováno v:
Leukemia & Lymphoma. 6:459-468
Proliferating cell nuclear antigen (PCNA) is the auxiliary protein of DNA polymerase δ It is induced in late G1 and S phases following mitotic stimulation of resting cells and is required for efficient DNA synthesis and cell cycle progression. Its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4976a694330cc5d8e09873b30eede621
https://doi.org/10.3109/10428199209053584
https://doi.org/10.3109/10428199209053584
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The identification of biomarkers (both molecules and profiles) in patient sera offers enormous interest for the diagnosis of cancers. In this context, the detection of anti-bodies to tumor cell autologous antigens possesses great potential. The humor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fbc6f46433f2aa6ab7275970acab4d
http://hdl.handle.net/10261/60664
http://hdl.handle.net/10261/60664
