Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sam Kazer"'
Autor:
Peter Keller, Irina Mazo, Yun Gao, Vijayapal Reddy, Francisco Caballero, Sam Kazer, Dannah Miller, Roberto Gianani, James E. Marvin, Bret Stephens, Gregory L. Beatty, Ulrich H. von Andrian, Thorsten R. Mempel
Publikováno v:
Molecular Cancer Therapeutics. 20:P106-P106
Background Despite transforming effects of immune checkpoint blockade (ICB) therapy, objective response rates are low for most solid tumors. In the tumor microenvironment (TME), regulatory T cells are functionally unstable, likely due to changes in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e698dde840a990ee32bf7546a156ed50
https://doi.org/10.1158/1535-7163.targ-21-p106
https://doi.org/10.1158/1535-7163.targ-21-p106
Autor:
James Marvin, Gregory Beatty, Yi Sun, Ulrich H. von Andrian, Amina Fu, Bret Stephens, Thorsten R. Mempel, Daniel Krappmann, Irina B. Mazo, Yun Gao, Peter Keller, Russell W. Jenkins, Roberto Gianani, Dannah Miller, Francisco Caballero, Vijayapal Reddy, Sam Kazer
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A902-A902
BackgroundMALT1 protease is a promising target in aggressive lymphomas1, and two phase 1 clinical trials in hematological cancers are ongoing (NCT03900598, NCT04876092). More recently, MALT1 protease inhibition was also shown to reprogram regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802db4989cffa59ff86a8683059f1a90
https://doi.org/10.1136/jitc-2021-sitc2021.861
https://doi.org/10.1136/jitc-2021-sitc2021.861