Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Sam Kacew"'
Autor:
Esref Demir, Sam Kacew
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 555 (2023)
Humans and animals may be exposed on a continuous daily basis to a mixture of environmental contaminants that may act on several organ systems through differing mechanisms [...]
Externí odkaz:
https://doaj.org/article/f0ff424d83f44414aaeddae96e8de5b0
Autor:
Esref Demir, Sam Kacew
Publikováno v:
Toxics, Vol 11, Iss 8, p 682 (2023)
Autophagy is the process through which a body breaks down and recycles its own cellular components, primarily inside lysosomes. It is a cellular response to starvation and stress, which plays decisive roles in various biological processes such as sen
Externí odkaz:
https://doaj.org/article/59b9dba06d0e413a90063c34b6c1f676
Autor:
Amit Kundu, Sreevarsha Gali, Swati Sharma, Jae Hyeon Park, So Young Kyung, Sam Kacew, In Su Kim, Kwang Youl Lee, Hyung Sik Kim
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1812 (2022)
High-fat diet (HFD)-induced obesity has been involved in the development of diabetic nephropathy (DN). Tenovin-1, a potent selective SIRT1/2 inhibitor, regulates various target proteins. The present study evaluated the protective effect of Tenovin-1
Externí odkaz:
https://doaj.org/article/7b9ffd6efc064f76a31e219cb7785820
Autor:
Tonancy Nicolás-Méndez, Sam Kacew, Alda Rocío Ortiz-Muñiz, Víctor Manuel Mendoza-Núñez, María del Carmen García-Rodríguez
Publikováno v:
Molecules, Vol 27, Iss 13, p 4028 (2022)
The aim of this study is to examine the ability of resveratrol to counteract hexavalent chromium [Cr(VI)]-induced genetic damage, as well as the possible pathways associated with this protection. Hsd:ICR male mice are divided into groups of the follo
Externí odkaz:
https://doaj.org/article/8dbeef47a04d4136897344b0cfca8e2d
Autor:
Yong Hee Lee, Ji Yeon Son, Kyeong Seok Kim, Yoo Jung Park, Hae Ri Kim, Jae Hyeon Park, Kyu-Bong Kim, Kwang Youl Lee, Keon Wook Kang, In Su Kim, Sam Kacew, Byung Mu Lee, Hyung Sik Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3709 (2019)
Hepatic fibrosis is characterized by persistent deposition of extracellular matrix proteins and occurs in chronic liver diseases. The aim of the present study is to investigate whether estrogen deficiency (ED) potentiates hepatic fibrosis in a thioac
Externí odkaz:
https://doaj.org/article/438d25df0839411e976749e528a7332d
Autor:
Gio B. Gori, Michael Aschner, Christopher J. Borgert, Samuel M. Cohen, Daniel R. Dietrich, Corrado L. Galli, Helmut Greim, John S. Heslop-Harrison, Sam Kacew, Norbert E. Kaminski, James E. Klaunig, Hans W.J. Marquardt, Olavi Pelkonen, Ruth Roberts, Kai M. Savolainen, Aristidis Tsatsakis, Hiroshi Yamazaki
Publikováno v:
Archives of Toxicology. 97:1813-1822
The 1958 Delaney amendment to the Federal Food Drug and Cosmetics Act prohibited food additives causing cancer in animals by appropriate tests. Regulators responded by adopting chronic lifetime cancer tests in rodents, soon challenged as inappropriat
Autor:
Amit Kundu, Sreevarsha Gali, Swati Sharma, Sam Kacew, Sungpil Yoon, Hye Gwang Jeong, Jong Hwan Kwak, Hyung Sik Kim
Publikováno v:
International Journal of Biological Sciences. 19:2630-2647
Autor:
H. M. Bolt, Helmut Greim, Christopher J. Borgert, Daniel R. Dietrich, Emanuela Testai, Pat Heslop-Harrison, Hans Marquardt, Alan R. Boobis, Olavi Pelkonen, Bas J. Blaauboer, Angela Mally, Gio Batta Gori, Sam Kacew, Corrado L. Galli, Jan G. Hengstler, José L. Domingo, Wolfgang Dekant, Kai Savolainen, Nico P. E. Vermeulen, Sir Colin Berry, Frank A. Barile, Aristides M. Tsatsakis
Publikováno v:
Barile, F A, Berry, S C, Blaauboer, B, Boobis, A, Bolt, H M, Borgert, C, Dekant, W, Dietrich, D, Domingo, J L, Galli, C L, Gori, G B, Greim, H, Hengstler, J G, Heslop-Harrison, P, Kacew, S, Marquardt, H, Mally, A, Pelkonen, O, Savolainen, K, Testai, E, Tsatsakis, A & Vermeulen, N P 2021, ' The EU chemicals strategy for sustainability: in support of the BfR position ', Archives of Toxicology, vol. 95, no. 9, pp. 3133-3136 . https://doi.org/10.1007/s00204-021-03125-w
Archives of Toxicology, 95(9), 3133-3136. Springer Verlag
Archives of Toxicology
Archives of Toxicology, 95(9), 3133-3136. Springer Verlag
Archives of Toxicology
The EU chemicals strategy for sustainability (CSS) asserts that both human health and the environment are presently threatened and that further regulation is necessary. In a recent Guest Editorial, members of the German competent authority for risk a
Publikováno v:
Journal of Toxicology and Environmental Health, Part B. 24:137-161
Risk assessment of cosmetic ingredients is a useful scientific method to characterize potential adverse effects resulting from using cosmetics. The process of risk assessment consists of four steps: hazard identification, dose-response assessment, ex
Publikováno v:
Current Opinion in Toxicology. 22:19-24
Flame retardants are widely used in electronic equipment, construction materials, and furniture to prevent fires from starting and to slow progression. Environmental monitoring studies show their presence in house dust, biomonitoring studies occasion